The importance of exercise for glycemic control in type 2 diabetes

Syeda, U.S. Afsheen; Battillo, Daniel J.; Visaria, Aayush; Malin, Steven K.

doi:10.1016/j.ajmo.2023.100031

Cited by 37 publications

(12 citation statements)

References 147 publications

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“…Advanced glycation end products (AGEs) result from multiple sugar-dependent reactions interacting with proteins and their receptors, generating endothelial dysfunction and CVD (ROBLES-RIVERA et al, 2023). On the other hand, physical exercise has been identified as a first-line therapy for patients with type 2 diabetes (T2DM), because, regardless exercise, intensity and duration, increased physical activity levels can promote better glycemic control in short and long term (SYEDA et al, 2023).…”

Section: Discussionmentioning

confidence: 99%

Chronic effect of bioresonance therapy on cardiovascular risk factors and physical activity pattern in the elderly: a randomized clinical trial

Mattera

Candeloro

Mora³

et al. 2023

CLIUM

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The aim of the study was to analyze the effect of 12 months of bioresonance therapy on physical activity behavior and cardiovascular risk factors in the elderly. A randomized, parallel, double-blind clinical trial was carried out in a sample of 20 elderly people. Bioresonance therapy was performed using QUANTEC® PRO. Data on gender, sex and morbidities were obtained. As cardiovascular risk factors, body composition, blood pressure and biochemical profile were analyzed. The behavior change stage related to physical activity was verified by the transtheoretical model and the physical activity pattern evaluated by the Baecke questionnaire. The treatment group showed a significant reduction in total cholesterol, triglycerides, blood glucose, LDL-c and non-HDL-c, and an increase in HDL-c and physical activity and physical exercise scores. The placebo group, showed a regression in the behavior stage for physical activity. Based on the results, we conclude that instrumental biocommunication therapy using QUANTEC® can make a significant contribution to the health of the elderly, particularly in increasing physical activity level, maintaining blood glucose levels and improving the lipid profile.

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Section: Discussionmentioning

confidence: 99%

Chronic effect of bioresonance therapy on cardiovascular risk factors and physical activity pattern in the elderly: a randomized clinical trial

Mattera

Candeloro

Mora³

et al. 2023

CLIUM

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“…Physical activity (PA) and/or exercise are essential for improving glucose levels and other cardiometabolic risk factors [1]. Prolonged time spent engaging in sedentary behaviors is associated with negative metabolic outcomes [2], which contribute to the occurrence and development of cardiovascular disease and type 2 diabetes mellitus (T2DM) [3].…”

Section: Introductionmentioning

confidence: 99%

“…Previous research has shown that activities contributing to glucose control include taking breaks during prolonged sitting, scheduling post-meal workouts to prevent hyperglycemia, and performing aerobic and/or resistance exercise (RE) [1]. One review [10] found that PA breaks (proving better than energy-matched continuous exercise) moderately attenuated glucose, insulin, and triacylglycerol, with greater glycemic attenuation in people with a higher body mass index.…”

Section: Introductionmentioning

confidence: 99%

“…Transient exaggerated spikes in glucose and lipids after meals may promote oxidative stress, triggering a biochemical inflammatory cascade that creates an environment conducive to the development of cardiovascular disease [11]. There are many randomized controlled trials (RCTs) studying the acute metabolic response of PA interruption, but there are few reviews on the optimal type, frequency, intensity, and duration of exercise required to reduce glucose and other metabolic markers; therefore, the optimal mode of exercise remains unclear [1]. Overall, the most important factors are those that influence exercise fuel metabolism, as well as the intensity and duration of PA [8].…”

Section: Introductionmentioning

confidence: 99%

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Impact of Prolonged Sitting Interruption on Blood Glucose, Insulin and Triacylglycerol in Adults: A Systematic Review and Meta-Analysis

Dong,

Pan,

Zhang

et al. 2024

Applied Sciences

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Background: Physical activity (PA) and/or exercise improves postprandial cardiometabolic risk markers; however, the optimal exercise intensity, frequency, and dose remain unclear. We aimed to (1) compare the acute metabolic effects of interrupted prolonged sitting with PA bouts of different frequencies and durations on blood glucose, insulin, and triacylglycerol responses, and (2) compare the effects of the different types and different times of PA breaks on these measures. Methods: A literature search was carried out using four databases. Network meta-analysis (NMA) and paired meta-analysis were performed to estimate the total standardized mean differences (SMDs) with 95% confidence intervals (95%CI). Results: According to the NMA, compared to prolonged sitting, every 30 min interruption had the highest probability (SUCRA) of being the best intervention for improving blood glucose (SUCRA = 81.8%, SMD = −1.18, 95%CI: −1.72, −0.64) and insulin (SUCRA = 77.5%, SMD = −0.98, 95%CI: −1.36, −0.60). Additionally, every 20 min interruption also significantly lowered blood glucose (SMD = −0.89, 95%CI: −1.52, −0.27) and insulin (SMD = −0.94, 95%CI: −1.41, −0.46). Pairwise meta-analysis suggested that frequent breaks by light-intensity PA significantly lowered glucose (SMD = −1.45, 95%CI: −2.32, −0.57) and insulin (SMD = −1.04, 95%CI: −1.53, −0.55). The same was found for frequent breaks by moderate-to-vigorous PA, which also significantly lowered glucose (SMD = −0.6, 95%CI: −0.83, −0.37) and insulin (SMD = −0.53, 95%CI: −0.73, −0.32). Conclusions: According to the NMA, performing short bouts of PA every 30 min is the most effective prolonged sitting intervention for improving blood glucose and insulin. More evidence is needed to determine the optimal type and time of PA breaks for braking sedentary sitting. PROSPERO Registration: CRD42022340036.

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“…Time-dependent exercise has different outcomes, 19 as shown by the greater increases in endurance capacity gained by evening exercise compared to morning exercise, 20 and the better glycemic control and weight control in obese and overweight individuals due to evening exercise. 21 , 22 , 23 , 24 , 25 ( Table 1 ) Moderate to vigorous exercise is more effective in the evening where it reduced insulin resistance by 25%. 26 Exercise in the afternoon by patients at risk of diabetes experienced superior benefits on peripheral insulin sensitivity, fasting plasma glucose levels, exercise performance, increased fatty acid oxidation, and fat mass loss.…”

Section: Introductionmentioning

confidence: 99%