2011
DOI: 10.1016/j.jana.2011.08.015
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The Importance of HIV Status and Gender When Designing Prevention Strategies for Anal Cancer

Abstract: Our objective is to review and summarize relevant aspects of the literature regarding human papillomavirus (HPV), the most common sexually transmitted infection in the United States, and to compare how the trajectory of HPV may differ in persons who are and who are not co-infected with HIV. This comparison is particularly important because the literature on HPV has been largely based on individuals who are not co-infected with HIV. Also, HPV findings may differ in HIV-uninfected individuals versus HIV-infected… Show more

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Cited by 4 publications
(2 citation statements)
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“…The significant diversity and high prevalence of multiple carcinogenic HPV infections complicates a fuller understanding of the role and risk of individual HPV genotypes in anal carcinogenesis among HIV-infected MSM, for whom the need for anal cancer prevention is the highest [13,14]. The clarification of the role of these individual genotypes can allow estimation of the efficacy of prophylactic vaccines, as well as inform the spectrum of HPV genotypes for future HPV-based screening assays [15].…”
Section: Discussionmentioning
confidence: 99%
“…The significant diversity and high prevalence of multiple carcinogenic HPV infections complicates a fuller understanding of the role and risk of individual HPV genotypes in anal carcinogenesis among HIV-infected MSM, for whom the need for anal cancer prevention is the highest [13,14]. The clarification of the role of these individual genotypes can allow estimation of the efficacy of prophylactic vaccines, as well as inform the spectrum of HPV genotypes for future HPV-based screening assays [15].…”
Section: Discussionmentioning
confidence: 99%
“…Current evidence concerning the acceptability of anal cancer screening in HIV-infected persons has also focused on men who have sex with men (Reed, Reiter, Smith, Palefsky, & Brewer, 2010), with less attention given to women (Ferron et al, 2011; Miguez, Burbano-Levy, Rosenberg, & Malow, 2011). Since HIV-infected women have a high prevalence of depression and significant history of trauma and sexual violence (Kimerling et al, 1999; Machtinger, Wilson, Haberer, & Weiss, 2012; McIntosh & Rosselli, 2012), understanding acceptability of anal cancer screening and willingness to participate in needed research involving concurrent testing with HRA among this group is critical to designing patient-centered screening programs.…”
Section: Introductionmentioning
confidence: 99%