1993
DOI: 10.1177/000331979304400606
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The Importance of the Subfascial Lymphatics in the Diagnosis of Lower Limb Edema: Investigations with Semiquantitative Lymphoscintigraphy

Abstract: A new method of semiquantitative lymphoscintigraphy for the evaluation of lower limb edema is characterized by (1) the evaluation of both the epifascial and subfascial system in order to assess type and stage of the edema, (2) the use of high-resolution digital whole-body imaging to facilitate the calculation of functional parameters, and (3) the use of active, standardized ergometry for reproducibility. The appearance time of 99mTc-labeled human albumin nanocolloid in inguinal lymph nodes after injection and … Show more

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Cited by 37 publications
(32 citation statements)
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“…This approach yields high numbers of T cells, and assessment of T cell responses in the SIN has been more sensitive than assessing those responses in PBMC [28]. There has been limited prior experience mapping lymphatic drainage from muscle [41,42]. The present study is, to our knowledge, the first to test whether i.m.…”
Section: Discussionmentioning
confidence: 99%
“…This approach yields high numbers of T cells, and assessment of T cell responses in the SIN has been more sensitive than assessing those responses in PBMC [28]. There has been limited prior experience mapping lymphatic drainage from muscle [41,42]. The present study is, to our knowledge, the first to test whether i.m.…”
Section: Discussionmentioning
confidence: 99%
“…In pure lipoedema, there is no change or only small changes in lymph transport (37). At an early stage before the occurrence of high-volume insufficiency, elevated lymph node uptake values can be measured with lymphoscintigraphy (38).…”
Section: Aetiologymentioning
confidence: 99%
“…Die Diskrepanz der geringeren sub-im Vergleich zur epifaszialen Mitreaktion im Sinne einer Hochvolumeninsuffizienz kann darin liegen, daß die interstitielle Flüßigkeitsvermeh-rung vom subfaszialen Lymphgefäßsy-stem schlechter toleriert wird und dadurch früher die Lymphtransportkapazität abnimmt als im epifaszialen Kompartiment. Hierfür könnten ähn-liche Mechanismen wie beim primä-ren Lymphödem verantwortlich sein, die dann zu einer Art subklinischem Kompartmentsyndrom führen könn-ten [5,6].…”
Section: Die Mitreaktion Des Lymphsystems Beim Primär Nicht Lymphödemunclassified
“…Subfaszial weisen alle Patienten einen massiv reduzierten Lymphtransport auf [5]. Zu diesem Ergebnis kamen auch Lofferer [13] und Tiedjen [21].…”
Section: Die Mitreaktion Des Lymphsystems Beim Primär Nicht Lymphödemunclassified