2021
DOI: 10.1016/j.ijoa.2021.102983
|View full text |Cite|
|
Sign up to set email alerts
|

The incidence, aetiology, and coagulation management of massive postpartum haemorrhage: a two-year national prospective cohort study

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1
1
1

Citation Types

0
17
0
1

Year Published

2022
2022
2024
2024

Publication Types

Select...
6

Relationship

0
6

Authors

Journals

citations
Cited by 26 publications
(18 citation statements)
references
References 28 publications
0
17
0
1
Order By: Relevance
“…40,52,53 When bleeding was not controlled with obstetric intervention with bleeds of !2,500 mL, the rate of fibrinogen of <2 g/L and/or Fibtem <12 mm was 14%, which was lower than the average of 17% in the whole cohort. 49 In cases of genital tract and/or surgical trauma, findings are similar, with a first fibrinogen <2 g/L in 1.6% of PPH >1,000 mL, and in bleeds >2,500 mL the rate of fibrinogen of Thromboelastography for Management of Postpartum Hemorrhage Collis, Bell <2 g/L and/or Fibtem A5 <12 mm was 14.6%, again lower than the overall cohort average of 17%. 49 In very massive bleeds, median first and worst platelet count, PT, and aPTT were all less abnormal when compared with the overall cohort, with presentation fibrinogen levels <2 g/L in only 20%, first platelet count <75 Â 10 9 /L in <10%, and first PT !16 seconds in <20%.…”
Section: Uterine Atony/traumamentioning
confidence: 77%
See 2 more Smart Citations
“…40,52,53 When bleeding was not controlled with obstetric intervention with bleeds of !2,500 mL, the rate of fibrinogen of <2 g/L and/or Fibtem <12 mm was 14%, which was lower than the average of 17% in the whole cohort. 49 In cases of genital tract and/or surgical trauma, findings are similar, with a first fibrinogen <2 g/L in 1.6% of PPH >1,000 mL, and in bleeds >2,500 mL the rate of fibrinogen of Thromboelastography for Management of Postpartum Hemorrhage Collis, Bell <2 g/L and/or Fibtem A5 <12 mm was 14.6%, again lower than the overall cohort average of 17%. 49 In very massive bleeds, median first and worst platelet count, PT, and aPTT were all less abnormal when compared with the overall cohort, with presentation fibrinogen levels <2 g/L in only 20%, first platelet count <75 Â 10 9 /L in <10%, and first PT !16 seconds in <20%.…”
Section: Uterine Atony/traumamentioning
confidence: 77%
“…33 Four PPH studies defining massive PPH as requiring RBC transfusion !4 units reported an incidence of lowest fibrinogen levels of <2 g/L in >24% of cases. 14,[47][48][49] A reduction in platelet count and prolongation of aPTT/PT were also reported, although only a minority reached treatment levels (platelets <75 Â 10 9 /L in 5% and PT/aPTT >1.5Â reference range in 3%). 49 In a very severe cohort requiring !8 units RBC transfusion, >60% developed plasma fibrinogen <2 g/L at some time during the bleed.…”
Section: Coagulopathy Rate By Pph Volumementioning
confidence: 98%
See 1 more Smart Citation
“…Bootstrapping was used to obtain confidence intervals for means and incremental costs. Additional analysis in clinical papers [3][4][5] includes changes in clinical outcomes using linear regression [4] and interrupted time series for massive PPH [4]. The cost model was completed using Microsoft Excel (2013).…”
Section: Discussionmentioning
confidence: 99%
“…The project finished in April 2019 and was subsequently adopted as standard PPH care across Wales [2]. The OBS Cymru design, implementation and outcomes have been published [3][4][5].…”
Section: Introductionmentioning
confidence: 99%