The incidence and body site of skin cancers in the population groups of Astana, Kazakhstan

McLoone, Pauline; McLoone, Philip; Imanbayev, Khalel; Norval, Mary

doi:10.1002/hsr2.51

Cited by 4 publications

(2 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Factors that significantly determine individual UV exposure are skin type, geographical location of residence, leisure time behaviour and occupational exposure. With regard to skin type, there are no known differences between resettlers and Germans; both are assigned to the Caucasian skin type [ 20 ].…”

Section: Discussionmentioning

confidence: 99%

“…In addition to time of year and day, the UV index depends mainly on latitude and is directly associated with the risk of NMSC [ 23 – 25 ]. The most frequent tumour localisations of BCC and SCC were reported in the head and neck region among Astana residents [ 20 ]. As for climatic conditions in Russia, it is not possible to generalise due to the size of the country.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Non-melanoma skin cancer among ethnic German immigrants (resettler) from the former Soviet Union: a cohort study from 1990 to 2007

et al. 2022

View full text Add to dashboard Cite

Background UV radiation is a significant risk factor for non-melanoma skin cancer (NMSC). Ethnic Germans (resettlers) who immigrated to Germany from the former Soviet Union may have had a relatively high UV light exposure and thus a higher risk of developing NMSC. We compared the incidence of NMSC in a resettler cohort with the general population of the Saarland (Federal state of Germany) in relation to tumour location. Methods All new NMSC cases (resettler cohort and total population) between 1990 and 2007 were retrieved from the Saarland cancer registry and classified according to sex, histology, and location. The classification used for tumour location approximated the previous UV exposure. Age-standardized incidence rates (ASR) for the general population and standardized incidence ratios (SIR) for resettlers compared to the general population were calculated and modelled using Poisson regression. Results Sex-specific overall SIR indicated a significant increase in female resettlers (SIR 1.31 (95% CI 1.02–1.67)) which can mostly be attributed to an increased incidence of squamous cell carcinoma. The regression analysis showed that among resettlers the risk of developing tumours in UV-exposed skin areas was 2.16 (95% CI 1.35–3.45) higher compared to the general population. Conclusions Female resettlers have a higher risk to be diagnosed with NMSC than the general German population. Based on the observed distribution of tumour location, it is suspected that UV exposure contributed significantly to this risk.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Non-melanoma skin cancer among ethnic German immigrants (resettler) from the former Soviet Union: a cohort study from 1990 to 2007

et al. 2022

View full text Add to dashboard Cite

show abstract

Convolutional neural network assistance significantly improves dermatologists’ diagnosis of cutaneous tumours using clinical images

Chen

et al. 2022

European Journal of Cancer

View full text Add to dashboard Cite

Engrailed Homeobox 1 and Cytokeratin 19 Are Independent Diagnostic Markers of Eccrine Porocarcinoma and Distinguish It From Squamous Cell Carcinoma

Miura¹,

Akashi

Namiki

et al. 2020

American Journal of Clinical Pathology

View full text Add to dashboard Cite

Objectives The diagnostic utility of En1 in the histopathologic differentiation of eccrine porocarcinoma (EPC) from invasive squamous cell carcinoma (SCC) was investigated. Methods Expression of En1 and CK19 in 16 cases of EPC was immunohistochemically examined and compared with that in 32 cases of SCC. Results In all 16 EPCs, En1 was expressed in 3% to 100% of tumor cells. In 20 of the 32 SCCs, En1 was expressed in 3% to 90% of tumor cells. A total of 13 of the 16 EPCs and five of the 32 SCCs were judged as En1 positive, with a cutoff value of 25%. In addition, 11 of the 16 EPCs and four of the 32 SCCs were CK19 positive. The frequencies of En1- and CK19-positive cases were significantly higher in EPCs than in SCCs. In a logistic regression analysis for predicting EPC, En1 and CK19 were independent markers. When expression patterns of En1 and CK19 were combined, none of the 32 SCCs was both positive. In contrast, 15 of the 16 EPCs were positive for either En1 or CK19. Conclusions A combination of En1 and CK19 expression can improve the accuracy of histologic diagnosis of EPC.

show abstract

The incidence and body site of skin cancers in the population groups of Astana, Kazakhstan

Abstract: Background and aims: Data on cutaneous malignant melanoma (CMM), squamous

Cited by 4 publications

References 18 publications

Non-melanoma skin cancer among ethnic German immigrants (resettler) from the former Soviet Union: a cohort study from 1990 to 2007

Non-melanoma skin cancer among ethnic German immigrants (resettler) from the former Soviet Union: a cohort study from 1990 to 2007

Convolutional neural network assistance significantly improves dermatologists’ diagnosis of cutaneous tumours using clinical images

Engrailed Homeobox 1 and Cytokeratin 19 Are Independent Diagnostic Markers of Eccrine Porocarcinoma and Distinguish It From Squamous Cell Carcinoma

Contact Info

Product

Resources

About