The Incidence and Epidemiology of Human Immunodeficiency Virus Infection in 320 Patients Treated in an Inner-City Hemodialysis Center

Reiser, Ira W.; Shapiro, Warren; Porush, Jerome G.

doi:10.1016/s0272-6386(12)80781-5

Cited by 21 publications

(11 citation statements)

References 10 publications

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“…Similarly, a poor survival for HIV-infected dialysis pa tients has been reported by Ortiz et al [14]. The overall survival rate for patients with HIV infection has signifi cantly improved, and more recently a number of investi gators have reported prolonged survival, even up to sever al years, for patients with HIV infection without AIDS who are on chronic hemodialysis [12] or on continuous ambulatory peritoneal dialysis [15,16]. Despite the ap parent overall improvement in survival for hemodialysis patients with HIV infection, many still do poorly on dialy sis and rapidly expire.…”

Section: Introductionmentioning

confidence: 73%

“…Of course, HIV-infected dialysis patients may have an etiolo gy for end-stage renal disease other than focal-segmental glomerulosclerosis, as in a significant number of HIVinfected patients with nephrotic syndrome glomerulone phritis has been found [8], Overall, the prevalence of HIV infection among chronic hemodialysis patients is esti mated at 1-2% [9,10]. In inner city areas, particularly in New York City and Miami, though, the prevalence is much higher [11,12].…”

Section: Introductionmentioning

confidence: 99%

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Predictors of Survival in HIV-Infected Patients on Hemodialysis

et al. 1996

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We undertook the present study to determine whether there might be variables other than CD4 counts which might help predict survival of HIV-infected patients who are placed on chronic hemodialysis, survival which often is extremely poor. We studied prospectively (n = 18) and retrospectively (n = 6) 24 consecutive HIV-positive patients on chronic hemodialysis at our institution over a 7-year period and recorded clinical and laboratory variables at the time of initiation of dialysis. The mean survival for the group as a whole was 11 ± 8 (range 2-32) months. A highly significant positive correlation was found between survival and CD4 counts (p < 0.001) and blood pressure (systolic, p < 0.02; diastolic, p < 0.05; mean arterial, p < 0.05). Infection rate and urine protein excretion both had significant negative correlations with survival (p < 0.01 and p < 0.02, respectively). The presence of edema appeared to have a positive effect on survival (p < 0.01). The use of antiretroviral therapy resulted in significantly greater survival of HIV-infected patients (15.2 ± 2.2 vs. 6.2 ± 1.2 months, p < 0.01). Using a general linear model, it was found that CD4 count and systolic, diastolic, and mean arterial blood pressures and infection rate all were independent estimators of survival. We conclude that variables other than CD4 counts might also be useful in predicting survival in HIV-infected patients on chronic hemodialysis.

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Section: Introductionmentioning

confidence: 73%

Section: Introductionmentioning

confidence: 99%

Predictors of Survival in HIV-Infected Patients on Hemodialysis

et al. 1996

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“…[22][23][24] A study from New York reported a 1 year survival rate of 16 % for dialysis patients with AIDS compared with a 77% survival rate for HIV seropositive patients without AIDS. 5 A similar picture is seen with peritoneal dialysis with survival being related to stage of HIV disease, although overall survival is poorer in HIV infected than non-infected patients.…”

Section: Discussionmentioning

confidence: 99%

Presentation, pathology, and outcome of HIV associated renal disease in a specialist centre for HIV/AIDS

Williams¹,

Williams²,

Williams³

et al. 1998

Sexually Transmitted Infections

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“…The HIV seroprevalence rate in dialysis units varies widely among different countries and within each country, depending on the geographic location of the unit and the demographics of patients treated. The prevalence of HIV infection in dialysis units ranged from 0 to 39% in early surveys (Table 4) (17)(18)(19)(20)(21)(22)(23)(24)(25)(26)(27)(28)(29)(30).…”

Section: Esrd In Hiv Diseasementioning

confidence: 99%

Human Immunodeficiency Virus Infection in End‐Stage Renal Disease Patients

Rao

2003

Seminars in Dialysis

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Human immunodeficiency virus (HIV) infection in patients with end-stage renal disease (ESRD) offers many diagnostic and therapeutic challenges to nephrologists. Renal failure may be a direct consequence of viral infection (HIV-associated nephropathy), or intrinsic renal diseases may occur in previously infected individuals. Patients receiving renal replacement therapy (RRT) may acquire HIV infection from blood transfusions, renal allografts, sexual contacts, or needle sharing by drug addicts. In the early 1980s, the overall prognosis of patients with the acquired immunodeficiency syndrome (AIDS) was very poor, and survival of those with ESRD was dismal. Consequently many even questioned the value of providing maintenance dialysis to patients with AIDS. With advances in diagnostic techniques in serologic and viral markers of disease, and deployment of highly effective antiretroviral agents, the prognosis of HIV-infected patients has dramatically improved. Over the past two decades, experiences in the management of HIV patients with ESRD is accumulating. Both peritoneal dialysis and hemodialysis are effective modes of therapy and many centers are now beginning to perform renal transplantation in HIV-infected patients. This article deals with various aspects of HIV infection in patients with ESRD.

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The Incidence and Epidemiology of Human Immunodeficiency Virus Infection in 320 Patients Treated in an Inner-City Hemodialysis Center

Cited by 21 publications

References 10 publications

Predictors of Survival in HIV-Infected Patients on Hemodialysis

Predictors of Survival in HIV-Infected Patients on Hemodialysis

Presentation, pathology, and outcome of HIV associated renal disease in a specialist centre for HIV/AIDS

Human Immunodeficiency Virus Infection in End‐Stage Renal Disease Patients

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