The incidence and nature of drug-related hospital admission: A 6-month observational study in a tertiary health care hospital

Abstract

Objective:To assess and evaluate the frequency, severity and classification of drug-related problems (DRP) resulting in hospitalization in an internal medicine department of a large tertiary care hospital and to identify any patient, prescriber, drug, and system factors associated with these events.Materials and Methods:A prospective and descriptive study carried out in Department of Medicine, Government Medical College, Jagdalpur. The DRP and relevant data were recorded on the personal record of every individual patient, filled during the course of treatment.Result:A total of 3560 patient’s records were analyzed. Among them118 admissions were due to DRP. The most common DRP noted was noncompliance in part of patient’s i.e 55 (46.6%). Statistically significant correlations were found in the number of prescribed drugs and over the counter drugs (OTC) used by patients.Conclusion:The DRP that attributed to hospital admission are mostly avoidable through proper patient education and strengthening the need of pharmacovigilance with little more vigilance in patient care.

A Pharmacovigilance Study Using Tracer Techniques

“…These findings were consistent with the literature reported by Ganachari et al and Singh et al [6,16].…”

Hospital admissions associated with medication non-adherence: a systematic review of prospective observational studies

“…In 21 studies2 19–22 24–29 31–39 41 (87.5%) employing combination measures, four different approaches for detection of non-adherence were identified: (1) a combined review of medical records and blood drug concentrations; (2) a combined review of medical records, drug concentrations and interview; (3) a combined review of medical records and interview; and (4) a combined review of medical records, interview and pill count. In 18 studies that reported definitions of medication non-adherence, four studies21 32 36 38 used the Haynes definition,42 one39 applied the WHO definition,1 one37 used Hepler and Strand,43 and the remaining studies created their own definitions. For the type of population, 17 studies19–21 23 24 26 28–30 33–39 41 were conducted on general populations, six in the elderly,2 25 27 31 32 40 and one in a paediatric population22 (table 1).…”

Drug-Related Hospital Visits and Admissions Associated with Laboratory or Physiologic Abnormalities—A Systematic-Review

“…While most documentation of the problem has focused on DRVs attributed to adverse drug reactions (ADRs), few researchers have explored other drug-related problem (DRP) etiologies categorized within the pharmaceutical care nosology, including inappropriate medication selection or dosing; untreated symptoms or disease; drug interactions; and patient non-adherence [1]–[5]. Features of patient populations at-risk for DRVs have been consistently described (the elderly, those with impaired cognition, dependent living situations, renal insufficiency, multiple comorbidities or polypharmacy) as have the most common offending therapies (antiplatelets, anticoagulants, non-steroidal anti-inflammatory drugs (NSAIDS), diuretics, angiotensin converting enzyme (ACE) inhibitors, opioids, and diabetes treatments) [6]–[8].…”