The incidence and risk factors of falls in Parkinson disease: prospective study

Rudzińska, Monika; Bukowczan, Sylwia; Stożek, Joanna; Zajdel, Katarzyna; Mirek, Elżbieta; Chwała, Wiesław; Wójcik-Pędziwiatr, Magdalena; Banaszkiewicz, Krzysztof; Szczudlik, Andrzej

doi:10.5114/ninp.2013.38223

Cited by 30 publications

(37 citation statements)

References 24 publications

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“…A high score in the Freezing of Gait Questionnaire, older age, and the presence of falls in medical history are independent risk factors for falls [50]. We found that the reduction in falls was greater after a long-term (e.g.…”

Section: Discussionmentioning

confidence: 69%

Efficacy and Safety of Tai Chi for Parkinson's Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Liu²,

et al. 2014

PLoS ONE

105

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Background and ObjectiveIn Parkinson's disease (PD), wearing off and side effects of long-term medication and complications pose challenges for neurologists. Although Tai Chi is beneficial for many illnesses, its efficacy for PD remains uncertain. The purpose of this review was to evaluate the efficacy and safety of Tai Chi for PD.MethodsRandomized controlled trials (RCTs) of Tai Chi for PD were electronically searched by the end of December 2013 and identified by two independent reviewers. The tool from the Cochrane Handbook 5.1 was used to assess the risk of bias. A standard meta-analysis was performed using RevMan 5.2 software.ResultsTen trials with PD of mild-to-moderate severity were included in the review, and nine trials (n = 409) were included in the meta-analysis. The risk of bias was generally high in the blinding of participants and personnel. Improvements in the Unified Parkinson's Disease Rating Scale Part III (mean difference (MD) −4.34, 95% confidence interval (CI) −6.67–−2.01), Berg Balance Scale (MD: 4.25, 95% CI: 2.83–5.66), functional reach test (MD: 3.89, 95% CI: 1.73–6.04), Timed Up and Go test (MD: −0.75, 95% CI: −1.30–−0.21), stride length (standardized MD: 0.56, 95% CI: 0.03–1.09), health-related quality of life (standardized MD: −1.10, 95% CI: −1.81–−0.39) and reduction of falls were greater after interventions with Tai Chi plus medication. Satisfaction and safety were high. Intervention with Tai Chi alone was more effective for only a few balance and mobility outcomes.ConclusionsTai Chi performed with medication resulted in promising gains in mobility and balance, and it was safe and popular among PD patients at an early stage of the disease. This provides a new evidence for PD management. More RCTs with larger sample size that carefully address blinding and prudently select outcomes are needed. PROSPERO registration number CRD42013004989.

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Section: Discussionmentioning

confidence: 69%

Efficacy and Safety of Tai Chi for Parkinson's Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Liu²,

et al. 2014

PLoS ONE

105

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“…Falls occur in approximately 50% of persons with PD, of which about 30% are injurious. 11,12 Postural instability has been identified as an independent predictor of falls in persons with PD, 13,14 and around one third of falls are caused by an unstable posture. 15 Current evidence suggests that PI is poorly responsive to general treatment options in persons with PD, such as medication with L-dopa and deep brain stimulation 16 ; some domains of balance dysfunction even worsen under pharmacological and surgical treatment.…”

Section: Introductionmentioning

confidence: 99%

Effects of Exercise Therapy on Postural Instability in Parkinson Disease

Klamroth¹,

Steib²,

Devan³

et al. 2016

Journal of Neurologic Physical Therapy

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Exercise therapies specifically addressing balance dysfunction are an important treatment option for improving postural stability in persons with PD. Future studies should investigate sustainability of the short-term effects and establish the dose-response relationship of balance training in persons with PD.Video abstract available for additional insights from the authors (see Video, Supplemental Digital Content 1, http://links.lww.com/JNPT/A121).

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“…The concomitant presence of classical gait dysfunction and dementia may increase the risk of falls in patients with PD, resulting in a worse outcome and increased hospitalisations 10 11. Considering that the prevalence of dementia in patients with PD reaches about 80% after 20 years and the ageing per se is one of the main risk factors for falls,12 specific treatments to interfere with the cholinergic and dopaminergic imbalance may improve the long-term outcome of patients with PD 13…”

Section: Introductionmentioning

confidence: 99%

Cholinesterase inhibitors for Parkinson's disease: a systematic review and meta-analysis

Pagano

Rengo

Pasqualetti

et al. 2014

J Neurol Neurosurg Psychiatry

108

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The incidence and risk factors of falls in Parkinson disease: prospective study

Abstract: Falls in PD patients occurred three times more frequently than in controls. Independent risk factors for falls were: high score in FOG-Q, older age and presence of falls in medical history.

Cited by 30 publications

References 24 publications

Efficacy and Safety of Tai Chi for Parkinson's Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Efficacy and Safety of Tai Chi for Parkinson's Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Effects of Exercise Therapy on Postural Instability in Parkinson Disease

Cholinesterase inhibitors for Parkinson's disease: a systematic review and meta-analysis

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