The incidence and the risk factors of venous thromboembolism in Korean patients with pelvic or acetabular fractures

Kim, Joon‐Woo; Oh, Chang Wug; Oh, Jong Keon; Baek, Seung Gil; Lee, Byoung Joo; Hong, Hoon Pyo; Min, Woo‐Kie

doi:10.1007/s00776-014-0553-z

Cited by 30 publications

(34 citation statements)

References 26 publications

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“…Only a few previous studies distinguished DVT in pelvic fractures or acetabular fractures. 6,11,26 Similar to the current study, Sen et al reported that the rate of DVT in acetabular fractures was higher than that in pelvic fractures (23.21% vs 5.36%). 12 In contrast, Kim et al did not find any difference between pelvic and acetabular fractures (32.7% vs 35%, respectively).…”

Section: Deep Vein Thrombosis Incidence Of Pelvic and Acetabular Fracturessupporting

confidence: 88%

“…Previous studies have shown that pelvic and acetabular fractures are associated with a broad spectrum of incidence of DVT (range: 2%-60%) and PE (range: 0.99%-21.74%; Table 4). 5,6,8,10,11,13,[22][23][24][25][26] In a study with 318 554 trauma patients, the incidence of PE in patients with pelvic fractures was 2 times higher than that in the overall trauma patients (0.6% vs 0.3%). 27 In our study, the incidence of Large amount of intraoperative blood transfusion means blood transfusion more than 1600 mL totally or transfusion faster than 1.5 mL/(kgÁmin).…”

Section: Deep Vein Thrombosis Incidence Of Pelvic and Acetabular Fracturesmentioning

confidence: 99%

“…Sen et al reported 17.85% (10/56), and Kim et al reported 9.47% (9/95). 11,12 Deep Vein Thrombosis in Pelvic Versus Acetabular Fractures…”

Section: Deep Vein Thrombosis Incidence Of Pelvic and Acetabular Fracturesmentioning

confidence: 99%

“…5,6 In the absence of thromboprophylaxis, the incidence of DVT in patients with pelvic fractures is variable, up to 61%, 7 while that of asymptomatic DVT is reported to be 15% to 68%. 8,9 However, even with anticoagulation, the incidence of DVT ranges from 3% to 30.5% in patients with pelvic and acetabular fractures, [10][11][12][13] with approximately 50% of those being pelvic (proximal) in origin. 14,15 While anticoagulation therapy is necessary to prevent VTE, it can cause bleeding and prolonged length of hospital stay or readmission, resulting in increased cost.…”

Section: Introductionmentioning

confidence: 99%

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Incidence and Risk Factors of Deep Vein Thrombosis in Patients With Pelvic and Acetabular Fractures

Wang

Kandemir

Zhang

et al. 2019

Clin Appl Thromb Hemost

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This study aimed to investigate the incidence and risk factors for deep vein thrombosis (DVT) in patients with pelvic and acetabular fractures. Patients with pelvic or acetabular fractures were included. Demographic data, fracture classification, time to surgery, and d -dimer levels at admission and one day after surgical intervention were recorded. Duplex ultrasonography was performed in the lower extremities for DVT evaluation. All patients received mechanical and chemical thromboprophylaxis. One hundred ten patients with a mean age of 44.2 ± 13.8 years were included. There were 48 patients with pelvic fractures and 62 patients with acetabular fractures. Thirty-two (29.09%) patients sustained DVT; 21 (19.09%) patients exhibited proximal thrombosis, and 3 patients suffered pulmonary embolism. The incidence of DVT in patients with acetabular fractures was significantly higher than that of patients with pelvic fractures (χ 2 = 4.42, P = .04). The incidence of proximal DVT was significantly higher in patients with complex acetabular fractures than in patients with simple acetabular fractures (χ 2 = 6.65, P = .01). Multivariate analysis showed that age older than 60 years, associated injuries, and the time to surgery longer than 2 weeks were independent risk factors ( P < .05). Despite mechanical and chemical thromboprophylaxis, the risk of DVT in patients with pelvic and acetabular fractures is still very high, and most of the thromboses were localized proximally. The risk of DVT is higher in patients older than 60 years, in those with associated injuries, and when the time from injury to operation is more than 2 weeks.

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Section: Deep Vein Thrombosis Incidence Of Pelvic and Acetabular Fracturessupporting

confidence: 88%

Section: Deep Vein Thrombosis Incidence Of Pelvic and Acetabular Fracturesmentioning

confidence: 99%

“…Sen et al reported 17.85% (10/56), and Kim et al reported 9.47% (9/95). 11,12 Deep Vein Thrombosis in Pelvic Versus Acetabular Fractures…”

Section: Deep Vein Thrombosis Incidence Of Pelvic and Acetabular Fracturesmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Incidence and Risk Factors of Deep Vein Thrombosis in Patients With Pelvic and Acetabular Fractures

Wang

Kandemir

Zhang

et al. 2019

Clin Appl Thromb Hemost

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“…Previous findings have shown that the CRP concentration in patients suffering bacterial infection is closely related to their trauma progression (13–15). If patients are successfully treated or their status improves, their CRP level is also reduced to normal level from high concentration.…”

Section: Discussionmentioning

confidence: 98%

The association between the levels of CRP, IL-10, PLA2, Fbg and prognosis in traumatic fracture of lower limb

Jiao

Wang

Xiao

et al. 2016

Experimental and Therapeutic Medicine

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The aim of the present study was to examine changes of sera levels of C-reactive protein (CRP), interleukin-10 (IL-10), phospholipase A2 (PLA2) and fibrinogen β polypeptide chain gene (Fbg) in patients with traumatic fracture of lower limb, and to evaluate their association with prognosis. The changes in sera levels of CRP, IL-10, PLA2 and Fbg were observed at the time of injury, 24 h, and 5 and 7 days after surgery in 90 patients with traumatic fracture of lower limb. In addition, 50 cases, who presented for health examination, were included as the normal controls. The expression of sera levels of CRP, IL-10, PLA2 and Fbg in patients with traumatic fracture of lower limb, was markedly higher than that in the normal controls prior to surgery (P<0.05). The concentration of CRP significantly increased within 24 h after emergency, but decreased gradually as the wound healed, compared to the controls. Pre- and postoperative IL-10 levels increased within 24 h and then decreased gradually. The level of PLA2 in patients before and after surgery was increased, and then decreased gradually. The level of Fbg in patients with trauma was increased after 24 h and then decreased, and increased gradually. The correlation of serum CRP and IL-10 levels (r=0.634, P<0.05), and that of PLA2 and IL-10 levels (r=0.617, P<0.05) were positive. In conclusion, the expression of CRP, IL-10, PLA2 and Fbg levels in traumatic fracture of lower limb markedly increased and was closely associated with prognosis. CRP, IL-10, PLA2 and Fbg levels may therefore serve as useful indexes in determining the progression and prognosis of patients with traumatic fracture of lower limb.

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Prophylactic inferior vena cava filters for operative pelvic fractures: a twelve year experience

Cohen-Levy

Liu

Sen

et al. 2019

International Orthopaedics (SICOT)

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The incidence and the risk factors of venous thromboembolism in Korean patients with pelvic or acetabular fractures

Cited by 30 publications

References 26 publications

Incidence and Risk Factors of Deep Vein Thrombosis in Patients With Pelvic and Acetabular Fractures

Incidence and Risk Factors of Deep Vein Thrombosis in Patients With Pelvic and Acetabular Fractures

The association between the levels of CRP, IL-10, PLA2, Fbg and prognosis in traumatic fracture of lower limb

Prophylactic inferior vena cava filters for operative pelvic fractures: a twelve year experience

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