The Incidence of Benign and Malignant Neoplasia Presenting as Acute Appendicitis

Sieren, Leah M.; Collins, Jay; Weireter, Leonard J.; Britt, Rebecca C.; Reed, Scott F.; Novosel, Timothy J.; Britt, L. D.

doi:10.1177/000313481007600822

Cited by 21 publications

(14 citation statements)

References 10 publications

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“…A large female preponderance is reported in all series (2-3:1) ( 38 , 39 ). In many studies diameter of carcinoid tumors were found to be shorter than 1 cm and dominantly located at the tip of the appendix ( 3 , 34 , 40 - 42 ). While tumor localization in our study was concordant with the literature, incidence seemed to vary with gender ( Table 3 ).…”

Section: Discussionmentioning

confidence: 99%

“…Appendectomy is the standard of care for mucinous cystadenoma, whereas a cystadenocarcinoma requires a right-sided hemicolectomy. Because of the high association of mucinous cystadenoma with colonic and ovarian malignancies, follow-up with CT-scans, ultrasonography, and colonoscopic examinations must be performed during the postoperative period ( 3 , 4 , 31 , 42 , 47 - 49 ).…”

Section: Discussionmentioning

confidence: 99%

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Unusual Findings in Appendectomy Specimens of Adults: Retrospective Analyses of 1466 Patients and a Review of Literature

Yabanoğlu¹,

Çalışkan²,

Aytaç³

et al. 2014

Iran Red Crescent Med J

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Background:Diseases and tumors of the appendix vermiformis are very rare, except acute appendicitis.Objectives:This retrospective study was conducted to document the unusual findings in appendectomy specimens.Patients and Methods:Data of 1466 adult patients were gathered retrospectively. Appendectomy was performed in 1169 and in 297 patients following a diagnosis of acute appendicitis and during other abdominal operations, respectively. The data of 57 (3.88 %) patients who were pathologically reported to have unusual appendix findings were retrospectively collected. The records were analyzed according to patients’ age, gender, clinical presentations, operative reports, pathological reports and follow up.Results:Unusual pathologic examination findings were detected in the appendectomy specimens of 57 patients with a mean age of 48.34 ± 19. Twenty-nine patients (50.8 %) were male and 28 (49.2 %) were female. Normal appendix tissues were observed in specimens of 26 (45.6 %) patients and inflamed appendix in 31 (54.3 %). The most common unusual finding was parasitic diseases of the intestine. Pathological diagnosis of malignancy and benign features were reported in specimens of 14 and 43 patients, respectively. Macroscopic evaluation of appendectomy specimens during surgery might result in negligence of the presence of unusual pathology.Conclusions:Even if the macroscopic appearance of the specimen is normal or acute appendicitis, we suggest routine histopathological examination.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Unusual Findings in Appendectomy Specimens of Adults: Retrospective Analyses of 1466 Patients and a Review of Literature

Yabanoğlu¹,

Çalışkan²,

Aytaç³

et al. 2014

Iran Red Crescent Med J

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“…Appendicular endometriosis is a rare pathology, usually diagnosed during operations for acute appendicitis [ 14 , 15 ]. This pathology has also been reported in patients with an incarcerated inguinal hernia [ 16 , 17 ].…”

Section: Discussionmentioning

confidence: 99%

Endometriosis of the Vermiform Appendix within a Hernia Sac Infiltrating the Pubic Bone

Ziaja

Bolkowski

Januszewski

et al. 2015

Case Reports in Surgery

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Purpose. Appendicular endometriosis mimicking appendicitis is a rare finding. Inguinal tumor in the course of appendicular endometriosis located within an inguinal hernia sac and infiltrating the periosteum of the pubic bone has not yet been described. Case Report. This paper describes a case of a rapidly enlarging, solid, unmovable, very painful upon palpation inguinal tumor, in a 36-year-old nulliparous woman. During surgery, a hard (approximately 4 cm in diameter) tumor infiltrating the periosteum of the right pubic bone and continuous with the inguinal hernia sac was dissected. The distal segment of the vermiform appendix was an element of the dissected tumor. Histological examination revealed endometriosis of the distal vermiform appendix. After 6 months of hormone treatment, she was referred for reoperation due to tumor recurrence. Once again histological examination of the resected tissue revealed endometriosis. There was no further recurrence of the disease with goserelin therapy. In addition to the case report, we present a review of the literature about endometriosis involving the vermiform appendix and the inguinal canal (Amyand's hernia). Conclusion. This case expands the list of differential diagnoses of nodules found in the inguinal region of women.

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“…Approximately, 25% of appendiceal mucinous neoplasms are asymptomatic and found incidentally either on abdominal imaging or during surgery. 8 Occasionally, these tumors may present with intestinal obstruction, intussusception, gastrointestinal bleeding and extrinsic ureteral compression. Rupture or perforation of the appendiceal wall, leads to dissemination of septic or neoplastic contents, resulting in localized or diffuse peritonitis or pseudomyxoma peritonei respectively.…”

Section: Discussionmentioning

confidence: 99%

Low Grade Appendiceal Mucinous Neoplasm with Pseudomyxoma Peritonei: An Enigma for Pathologist

Qadri

Alam

et al. 2014

Euroasian Journal of Hepato-Gastroenterology

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Malignant mucinous neoplasms of the appendix is an infrequently encountered entity. Extra-appendiceal spread of these tumor is one of the commonest etiology of pseudomyxoma peritonei, which demands a hightened vigilance in their early diagnosis. Although low-grade appendiceal mucinous neoplasms (LAMNs) largely stay confined to the appendix, but they can spread to the peritoneum as pseudomyxoma peritonei leading to an unpredictable outcome. Due to the rare occurrence of low-grade appendiceal neoplasm only tenuous and limited information is present in the medical literature. We report a case of LAMN with pseudomyxoma peritonei in a 45-year-old male, who presented with the complaints of abdominal distension associated with abdominal pain and constipation. Clinical examinations and computed tomography (CT) scan were suggestive of pseudomyxoma peritonei. Peroperative findings and histopathological examination rendered a conclusive diagnosis of low-grade appendiceal neoplasm.How to cite this article: Qadri S, Alam K, Alam F, Maheshwari V. Low Grade Appendiceal Muci-nous Neoplasm with Pseudomyxoma Peritonei: An Enigma for Pathologist. Euroasian J Hepato-Gastroenterol 2014;4(2):113-116.

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The Incidence of Benign and Malignant Neoplasia Presenting as Acute Appendicitis

Cited by 21 publications

References 10 publications

Unusual Findings in Appendectomy Specimens of Adults: Retrospective Analyses of 1466 Patients and a Review of Literature

Unusual Findings in Appendectomy Specimens of Adults: Retrospective Analyses of 1466 Patients and a Review of Literature

Endometriosis of the Vermiform Appendix within a Hernia Sac Infiltrating the Pubic Bone

Low Grade Appendiceal Mucinous Neoplasm with Pseudomyxoma Peritonei: An Enigma for Pathologist

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