The incidence of giant cell arteritis in Olmsted County, Minnesota, over a 60-year period 1950–2009

Chandran, Arun; Udayakumar, Prabhu D.; Crowson, Cynthia S.; Warrington, Kenneth J.; Matteson, Eric L.

doi:10.3109/03009742.2014.982701

Cited by 83 publications

(67 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Prior studies have indicated an annual incidence of GCA of 19.8 per 100,000. 29,30 Assuming 8.2–48.8% of these patients suffer permanent vision loss, 85% from A-ION as discussed above, the annual incidence of A-ION from GCA of 1.3 per 100,000 in the current study is likely closer to the actual incidence of this complication. The higher incidence in the current study may also reflect the population of Olmsted County, which is 90.3% Caucasian according to the 2000 US census data.…”

Section: Discussionmentioning

confidence: 50%

See 1 more Smart Citation

Evaluating the Incidence of Arteritic Ischemic Optic Neuropathy and Other Causes of Vision Loss from Giant Cell Arteritis

et al. 2016

View full text Add to dashboard Cite

Objective To determine the incidence of permanent visual loss from giant cell arteritis (GCA). Design Retrospective, population-based cohort Participants All residents of Olmsted Country, Minnesota, USA, diagnosed with GCA between January 1, 1950 and December 31, 2009 Methods All cases of GCA were identified using the Rochester Epidemiology Project, which is a record-linkage system of medical records for all patient-physician encounters among Olmsted County, Minnesota residents. The medical records were reviewed to identify and determine the cause of permanent vision loss among patients with GCA. Systemic symptoms of GCA and visual outcomes were also determined. Main Outcome Measures Incidence and outcomes of permanent vision loss from GCA. Results Among the 245 new cases of GCA over the 60-year period, 20 (8.2%) patients suffered permanent vision loss due to GCA. The frequency of arteritic ischemic optic neuropathy (A ION) was 6.9% (95%CI: 4.0%–11.1%) accounting for 85% of cases of permanent vision loss. The frequency of central retinal artery occlusion (CRAO) was 1.6% (95%CI: 0.4%–4.2%) and cilioretinal artery occlusion was 0.4% (95%CI: 0.01%–2.3%). The population-based age- and sex-adjusted annual incidence of A-ION from GCA among persons age ≥ 50 years was 1.3 (95%CI: 0.7–2.0) per 100,000 population. 20% of patients with permanent vision loss from GCA had vision loss without constitutional symptoms of GCA. Overall, there was no significant difference between presenting and final visual acuities. Conclusion This population-based data provides the most accurate incidence of permanent vision loss from GCA. This study confirms that visual outcomes from GCA-related vision loss are poor and that 20% of patients with permanent visual loss from GCA can present without systemic symptoms of GCA.

show abstract

Section: Discussionmentioning

confidence: 50%

“…22,29,30,33,34 Interesting, Johnson and Arnold found no sex predilection for A-ION in their incidence study. 28 …”

Section: Discussionmentioning

confidence: 87%

Evaluating the Incidence of Arteritic Ischemic Optic Neuropathy and Other Causes of Vision Loss from Giant Cell Arteritis

et al. 2016

View full text Add to dashboard Cite

show abstract

“…(6, 14) The diagnosis was based on 1990 American College of Rheumatology criteria for classification of GCA. (15) Patients aged ≥50 years with elevation of erythrocyte sedimentation rate (ESR) or C-reactive protein (CRP) and computed tomography/angiography, magnetic resonance arteriography or positron emission tomography evidence of large vessel vasculitis involving the ascending aorta and/or its branches were also included.…”

Section: Methodsmentioning

confidence: 99%

Contemporary prevalence estimates for giant cell arteritis and polymyalgia rheumatica, 2015

Crowson

Matteson

2017

Seminars in Arthritis and Rheumatism

View full text Add to dashboard Cite

Objective There are no estimates of the prevalence of giant cell arteritis (GCA) or polymyalgia rheumatica (PMR) in a US population in the current millennium. The purpose of this study was to estimate the 2015 prevalence of GCA and PMR in a US population-based setting. Methods Cohorts of incident GCA in 1950–2009 and incident PMR in 1970–2014 were previously identified among residents of Olmsted County, Minnesota. Prevalence estimates were obtained from the age-, sex- and calendar year-specific incidence rates and adjusted to the US white 2010 population aged ≥50 years. Confidence intervals [CI] were computed using bootstrap sampling. Results There were 248 incident cases of GCA in 1950–2009 and 790 cases of PMR in 1970–2014. The overall age- and sex-adjusted prevalence rate of GCA on January 1, 2015 was 204 (95% CI: 161–254) per 100,000 population aged ≥50 years. GCA prevalence rate in women was 304 (95%CI: 229–375) and in men was 91 (95%CI: 46–156) per 100,000 population. The overall age and sex adjusted prevalence rate of PMR on January 1, 2015 was 701 (95%CI: 651–750) per 100,000 population. PMR prevalence rate in women was 870 (95%CI: 787–957) and in men was 508 (95%CI: 426–589) per 100,000 population. Conclusion Prevalence rates of GCA and PMR in 2015 are similar to previously published prevalence estimates in the late 1990s. The health burden of these diseases among older persons continues to be substantial and reflects the need for continued efforts to better manage it.

show abstract

“…The GCA cohort consisted of patients who fulfilled the 1990 ACR criteria for GCA in 1950–2009. [9, 10]. …”

Section: Methodsmentioning

confidence: 99%

The Detection of Rheumatic Disease through Hospital Diagnoses with Examples of Rheumatoid Arthritis and Giant Cell Arteritis: What Are We Missing?

Michet

Crowson²,

Achenbach

et al. 2015

J Rheumatol

View full text Add to dashboard Cite

Objective We examined hospitalizations for patients with known rheumatoid arthritis (RA) or giant cell arteritis (GCA) to evaluate whether hospitalization-related diagnoses accurately capture patients with rheumatologic diseases. Methods Diagnosis codes for hospitalizations in 1996–2012 among previously identified population-based cohorts of RA/GCA patients were examined for RA/GCA mention. Results RA/GCA mention occurred in only 55% of 2407 hospitalizations among RA patients and 31% of 502 hospitalizations among GCA patients. RA/GCA was mentioned more often in recent years, younger patients and rheumatic medication users. Conclusion Coding for RA/GCA during hospitalizations was often missed. Research utilizing hospital diagnoses alone could be biased.

show abstract

The incidence of giant cell arteritis in Olmsted County, Minnesota, over a 60-year period 1950–2009

Cited by 83 publications

References 11 publications

Evaluating the Incidence of Arteritic Ischemic Optic Neuropathy and Other Causes of Vision Loss from Giant Cell Arteritis

Evaluating the Incidence of Arteritic Ischemic Optic Neuropathy and Other Causes of Vision Loss from Giant Cell Arteritis

Contemporary prevalence estimates for giant cell arteritis and polymyalgia rheumatica, 2015

The Detection of Rheumatic Disease through Hospital Diagnoses with Examples of Rheumatoid Arthritis and Giant Cell Arteritis: What Are We Missing?

Contact Info

Product

Resources

About