The Incidence of Isolated Craniosynostosis in the Newborn Infant

Shuper, Avinoam; Merlob, Paul; Grunebaum, Michael F.; Reisner, Salomon H.

doi:10.1001/archpedi.1985.02140030091038

Cited by 70 publications

(58 citation statements)

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“…The prevalence of any one of these fused sutures is approximately 1 in 2,000 live births (Shuper, Merlob, Grunebaum, & Reisner, 1985;Singer, Bower, Southall, & Goldblatt, 1999). One hypothesized correlate or consequence of SSC is brain deformation with associated neurodevelopmental impairment (Kapp-Simon, Speltz, Cunningham, Patel, & Tomita, 2007;Speltz, Kapp-Simon, Cunningham, Marsh, & Dawson, 2004).…”

Section: Introductionmentioning

confidence: 99%

Memory and Response Inhibition in Young Children with Single-Suture Craniosynostosis

Toth

Collett

Kapp-Simon

et al. 2008

Child Neuropsychology

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Using two versions of the A-not-B task, memory and response inhibition were assessed in 17-to 24-month-old children with surgically corrected single-suture craniosynostosis (cases) and unaffected children (controls). Children's development and language were initially assessed on average at 6-7 months of age and again at this second visit. Cases and controls performed at equivalent levels on average, with cases performing slightly better than controls on several of the variables measured. However, fewer cases than controls were able to complete the more challenging of the two tasks, which may have predictive significance for later functioning. Children's age and cognitive ability were related to successful performance on the A-not-B task. Among cases, age of cranioplastic surgery was unrelated to performance. Our findings suggest that children with single-suture craniosynostosis show normal development of visual memory and response inhibition in the age range studied here.

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Section: Introductionmentioning

confidence: 99%

Memory and Response Inhibition in Young Children with Single-Suture Craniosynostosis

Toth

Collett

Kapp-Simon

et al. 2008

Child Neuropsychology

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“…1,2 Corrective surgery to restore the suture is preferentially performed in the first year of life. Neurodevelopmental impairment has long been suspected among children with SSC, because the prematurely fused suture is believed to constrain 3 or alter 4,5 brain structures and elevate intracranial pressure.…”

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confidence: 99%

Intellectual and Academic Functioning of School-Age Children With Single-Suture Craniosynostosis

2015

PEDIATRICS

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We compared the developmental status of school-age children with single-suture craniosynostosis (case group) and unaffected children (control group). Within the case group we compared the performance of children distinguished by location of suture fusion (sagittal, metopic, unicoronal, lambdoid). METHODS:We administered standardized tests of intelligence, reading, spelling, and math to 182 case participants and 183 control participants. This sample represented 70% of those tested during infancy before case participants had corrective surgery. RESULTS:After adjustment for demographics, case participants' average scores were lower than those of control participants on all measures. The largest observed differences were in Full-Scale IQ and math computation, where case participants' adjusted mean scores were 2.5 to 4 points lower than those of control participants (Ps ranged from .002 to .09). Adjusted mean case-control differences on other measures of achievement were modest, although case deficits became more pronounced after adjustment for participation in developmental interventions. Among case participants, 58% had no discernible learning problem (score ,25th percentile on a standardized achievement test). Children with metopic, unicoronal, and lambdoid synostosis tended to score lower on most measures than did children with sagittal fusions (Ps ranged from ,.001 to .82). CONCLUSIONS:The developmental delays observed among infants with single-suture craniosynostosis are partially evident at school age, as manifested by lower average scores than those of control participants on measures of IQ and math. However, case participants' average scores were only slightly lower than those of control participants on reading and spelling measures, and the frequency of specific learning problems was comparable. Among case participants, those with unicoronal and lambdoid fusions appear to be the most neurodevelopmentally vulnerable.

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“…Чаще поражается правая половина коронарного шва [17]. При ГКС возникают уплощение верхнего края орбиты и лоб-ной кости на стороне поражения с компенсаторным на-висанием противоположной половины лба, ипсилате-ральное уплощение скуловой области и искривление носа в ту же сторону.…”

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