The Incidence of Left Atrial Appendage Thrombus in Warfarin Versus Noacs Prior to Transoesophageal Echocardiogram Guided Cardioversion

Abstract

The study was conducted as an external analysis of prospectively collected data from Stepathlon, an annual international mHealth based global event conducted in the years 2012-14. Participants were organised in worksite-based teams, issued pedometers, and encouraged to increase daily steps and physical activity via utilisation of a multi-platform app, functional on mobile devices and the internet. The main outcome measures were change in step count, exercise days, sitting duration and weight.Results: The study included n=62905 participants in LMICs, with complete follow-up data available from 32956 participants. Following Stepathlon completion, improvements were seen in step count (+3563 steps/day 95%CI: 3527-3600, P<0.0001), sitting duration (-0.73 hrs/day 95%CI:-0.75,-0.70,P<0.0001), exercise days/week (+0.91, 95%CI: 0.89,0.93,P<0.0001), and weight (-1.51kg, 95%CI: -1.59 to -1.43, P<0.0001). Improvements were seen in women, men, and each year cohort (all P<0.0001).Conclusion: Large scale Mobile Health lifestyle intervention in lower-middle income countries translates to a significant reduction in the cardiovascular risk factors of elevated body weight and physical inactivity.