The incidence of occult level IV nodal metastasis in tongue squamous cell carcinoma: a 20 year review

Abstract

Background The extent of neck dissection for tongue SCC is unclear owing to the potential presence of occult level IV metastasis. We aim to assess the incidence of occult level IV nodal metastasis for tongue SCC patients treated in our centre over a 20 year period. Methods A retrospective analysis of data collected from 1999 to 2019 was performed. Patients diagnosed with oral tongue SCC treated primarily with surgery and a neck dissection fulfilled the inclusion criteria. Results A total of 124 patients were included in our study. Sixty‐one patients were N0 with no occult level IV metastasis. About 17.3% of clinically node positive patients had level IV metastasis. Length of hospital stay and complication rates were comparable for patients who received levels I–III and I–IV neck dissections. Conclusion Occult level IV metastasis in N0 tongue SCC patients are exceedingly rare, we would therefore suggest consideration for a level I–III neck dissection. In patients who are clinically node positive, a level I–IV neck dissection would be recommended.

Histological depth of invasion and its correlation in oral squamous cell carcinoma- a retrospective study

“…Therefore, predicting the occult cervical lymph node metastases using the depth of invasion may be helpful. Similar investigations have shown that in cases of carcinomas of the lateral border of the tongue, level II nodes are the most frequently involved site, followed by level III nodes (6,18,19).…”

“…OSSC most commonly develops on the sites such as lips, tongue and floor of the mouth, while some OSCCs arise in apparently normal mucosa and some may be preceded by clinically obvious premalignant lesions like leukoplakia and erythroplakia (4,5). Typically, OSCC often presents as an ulcer with prominent exophytic margins or fissures (6). It can also develop as a lump, an enlarged, hard, or fixated cervical lymph node, a white or mixed white and red lesion, an extraction socket that won't heal, or a red lesion (erythroplakia) (7,8).…”