The Incidence of Phthisis Bulbi as a Complication of Cataract Surgery in the Congenital Rubella Syndrome

Boniuk, Vivien; Boniuk, Milton

doi:10.1097/00004397-197206000-00006

Cited by 2 publications

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“…Poor outcomes after cataract surgery in patients with rubella are documented in the literature. 22,23 Inflammation and incidence of pupillary membrane, posterior synechiae, and secondary glaucoma are increased in patients with CRS. These findings have been attributed to release of virus from the lens at the time of surgery and initiation of an immune reaction after cataract surgery.…”

Section: Commentmentioning

confidence: 99%

An Epidemiological and Clinical Study of Ocular Manifestations of CongenitalRubella Syndrome in Omani Children

et al. 2004

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Objective: To conduct a follow-up study in patients with congenital rubella syndrome (CRS) in Oman and analyze the prevalence of ophthalmic disorders and associated systemic problems. Methods: This historical prospective cohort study included review of 32 surviving patients with CRS reported by the surveillance system in Oman from 1987 through 2002. All patients underwent a complete ophthalmic examination that included visual acuity estimation, refraction and anterior and posterior segment evaluation, and intraocular pressure measurement. Pediatric and otorhinolaryngologic consultations were also performed. Results: The age-adjusted prevalence of CRS in Oman was 73.2 per million in the Omani population younger than 20 years, and the incidence was 0.6 per 1000 live births. Cataract, retinitis, microphthalmos, and glaucoma were observed in 11, 16, 6, and 4 patients, respectively. Keratoconus, corneal hydrops, and spontaneous resorption of lens were found in 1 patient each. Vision testing was possible in 16 children; 4 were bilaterally blind. Patients who had undergone eye surgery had significantly lower visual acuity, as compared with those who had not undergone surgery (relative risk 2.53; 95% confidence interval, 1.07-6.13). Among the 11 patients with CRS with cataract, we found hearing loss, cardiac anomalies, and neuropsychologic anomalies in 7, 4, and 6 children, respectively. Conclusions: Congenital rubella syndrome has a wide variety of severe ophthalmic and systemic complications. High clinical vigilance for signs of CRS and regular observation of surviving patients with CRS is desirable. In patients with cataract, the functional results of surgery, despite state-ofthe-art ophthalmic care, continue to be poor. Because of a high prevalence of visual, audiologic, and neurologic disabilities, surviving patients with CRS pose a burden on the medical and social communities. Emphasis in management ought to be prevention of CRS through effective immunization programs.

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Section: Commentmentioning

confidence: 99%

An Epidemiological and Clinical Study of Ocular Manifestations of CongenitalRubella Syndrome in Omani Children

et al. 2004

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“…Manual dexterity, tissue handling and surgical precision are key to achieving desired outcomes [3]. Poor surgical skills can result in devastating outcomes [4] including irreversible vision loss [5] [6] [7], or outright phthisis of the globe [8]. Ophthalmic surgical training has a steep learning curve [9] with large numbers required for increasing stepwise competence [9].…”

Section: Introductionmentioning

confidence: 99%

Cost-Effective Ophthalmic Surgical Wetlab Using the Porcine Orbit with a Simple Dissection Protocol

Ezeanosike¹,

Azu-Okeke²,

Achigbu³

et al. 2019

OJOph

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Objective: To describe the dissection protocol for the pig head to obtain the orbital tissue, as well as a simple setup for ophthalmic surgical wetlabs.Methods and Analysis: A descriptive study. The pig head dissection was performed at the abattoir for convenience. The orbital tissue thus obtained was used to set up the wetlab workstation. Results: A cost-effective, low technology, affordable set-up for ophthalmic surgical wetlab protocol was developed. High resolution photographs of the procedure were taken and were presented for ease of description. The dissection protocol was test-run at an ophthalmic surgical training workshop. Conclusions: The porcine orbit and the wetlab setup were available and affordable. The dissection in the abattoir is easy and reproducible. The orbit was used instead of the enucleated globe and this ensures stability throughout surgical practice sessions.

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The Incidence of Phthisis Bulbi as a Complication of Cataract Surgery in the Congenital Rubella Syndrome

Cited by 2 publications

References 0 publications

An Epidemiological and Clinical Study of Ocular Manifestations of CongenitalRubella Syndrome in Omani Children

An Epidemiological and Clinical Study of Ocular Manifestations of CongenitalRubella Syndrome in Omani Children

Cost-Effective Ophthalmic Surgical Wetlab Using the Porcine Orbit with a Simple Dissection Protocol

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