The incidence of postoperative re-stratification for recurrence in well-differentiated thyroid cancer—a retrospective cohort study

Neiderman, Narin N. Carmel; Duek, Irit; Ravia, Adi; Yaka, Rami; Warshavsky, Anton; Ringel, Barak; Muhanna, Nidal; Horowitz, Gilad; T, Baran; Fliss, Dan M.

doi:10.21037/gs-21-105

Cited by 2 publications

(1 citation statement)

References 32 publications

(52 reference statements)

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“…In a study including 30.180 papillary thyroid microcarcinoma (PTMC) cases, where CLND was performed in 52%, there was a 19% incidence of high-risk factors identified through pathological evaluation (11). In another study evaluating 301 low-risk PTC patients with tumor sizes between 1-4 cm, 15% of the patients transitioned from the low-risk group to the intermediate or high-risk group based on postoperative evaluation (25).…”

Section: Discussionmentioning

confidence: 99%

How good is lobectomy for the Turkish population with papillary thyroid cancer? A clinicopathological evaluation

Konca

2023

Turk J Surg

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Objective: In modern practice, there is an increasing recommendation for higher utilization of lobectomy in the management of papillary thyroid cancer (PTC). However, in this decision where the optimal balance of locoregional recurrence and complication burden should be achieved, there are still conflicting results in the literature. The aim of this study was to evaluate the effect of high-risk factors in the Turkish population with PTC on the decision of hypothetical lobectomy. Material and Methods: In this study, 96 PTC patients undergoing total thyroidectomy were retrospectively analyzed. Preoperative and postoperative evaluation differences and the impact of high-risk factors (tumor size, multifocality, extrathyroidal extension and central lymph node metastasis) on the decision for hypothetical lobectomy were investigated. Results: In all patients and lobectomy-eligible patients, postoperative evaluations of multifocality, contralateral multifocality, and central lymph node metastases were significantly higher than preoperative evaluations. Consequently, postoperative evaluation revealed that completion thyroidectomy would be required in 52.9% of 51 patients who were hypothetically suitable for lobectomy. Furthermore, comparisons of tumor size-based grouping in lobectomy and total thyroidectomy suitable patients showed similar high-risk factor distribution except for central lymph node metastasis for tumors <10 mm and contralateral multifocality between 11-20 mm. Conclusion: Completion thyroidectomy will be required in approximately half of the patients evaluated as suitable for lobectomy in the treatment of PTC in the Turkish population. In the treatment decision, in which many patient- and surgeon-related factors are influential, each patient should be considered separately.

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Section: Discussionmentioning

confidence: 99%