Aim : This study aimed to list the different risk factors for cranio-mandibular dysfunctions (CMD), and thus contribute to the creation of a database of the identified risk factors. Methods : The search strategy was run from September 1,2020 to March 31, 2021. The following electronic databases were searched: Embase, Scopus, Science Direct, PubMed, Cochrane Library. A total of 271 articles were screened by title and abstract, and 29 were assessed by full text. Ten articles met the eligibility criteria and were included in the systematic review. Results : This study aimed to explore the different risk factors for CMD. Our work targeted articles published between 2011 and 2021, in order to focus on recent scientific research. We divided these factors into 3 categories: general factors, psychosocial factors and dental factors. 5 studies were about general risk factors, 2 were about dental risk factors and 3 were about psychosocial factors. Conclusion : This systematic review addressed the main risk factors of DCM. The development of a precise classification of risk factors and the determination of the latter will offer practitioners the appropriate choice of treatments, and therefore the possibility of ensuring long-term management.