The Incidence Rate of Premature Rupture of Membranes and its Influence on Fetal-neonatal Health: A Report From Mainland China

Liu, Jing; Feng, Zhi Chun; Wu, Jing

doi:10.1093/tropej/fmp051

Cited by 49 publications

(39 citation statements)

References 16 publications

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“…We hypothesize that there are several reasons why this may be the case (10,19). 1-PROM leads to maternal-fetal infection; this occurs in nearly 1/3 of patients with PROM (20). Intrauterine infection and chorioamnionitis caused by PROM can result in direct injury to the fetal lungs and alveolar type II cells, decreasing the synthesis or release of surfactant.…”

Section: Discussionmentioning

confidence: 99%

High-risk Factors of Respiratory Distress Syndrome in Term Neonates: A Retrospective Case-control Study

2014

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Respiratory distress syndrome (RDS) is one of the most common causes of neonatal respiratory failure and neonatal death. The underlying pathogenesis of RDS involves developmental immaturity of the lungs, leading to inadequate pulmonary surfactant (PS) production. It was previously believed that RDS mainly occurs in premature infants (1); however, with the application of antenatal corticosteroids and delivery room PS, typical and severe RDS in premature infants is now rarely diagnosed. Greater awareness of RDS has led to a more frequent diagnosis in term neonates (2-5). However, the reasons for the occurrence of RDS in term neonates are different from those in premature infants, and remain unclear. This study aimed to investigate the cause of RDS in full-term neonates by a retrospective case-control study, and thus provide a useful reference for its diagnosis and treatment. MATERIAL AND METHODSThis investigation was approved by the ethics committee of the Beijing Military General Hospital. In this retrospective case-control study, the proportion of the case group (RDS patients) and control group (RDS-free patients) was 1:2. The following information was recorded: mode of delivery, birth asphyxia, premature rupture of membranes (PROM), maternal age at pregnancy, pregnancy hypertension disease, gestational glucose intolerance or diabetes, sex, birth weight, a cord around the neck with compression, oligohydramnios, meconium staining of amniotic fluid, severe fetal distress, and placental abruption.From January 2008 to December 2010, a total of 205 full-term newborns with RDS who were admitted to the Department of Neonatology & Neonatal Intensive Care Unit (NICU) (the largest NICU in the world with 350 beds; there are about 8,000 newborn infants admitted to this NICU within one year) at Bayi Children's Hospital, affiliated with the Beijing Military General Hospital of the Beijing Military Command, were assigned to this study. The diagnosis of term neonatal RDS met the following criteria (2-5): (1) full-term neonates (gestational age ≥37 weeks); (2) acute onset; (3) an acute, explicit perinatal triggering insult, such as severe perinatal acquired infection, severe birth asphyxia, meconium aspiration syndrome, or delivery by selective cesarean section; (4) representative clinical manifestations, including progressive respiratory distress occurring shortly after birth, tachypnea, expiratory grunting, nasal flaring, Background: Respiratory distress syndrome (RDS) is a common critical disease in term neonates, but reasons for the occurrence of RDS remains unclear. Aims: This study aimed to investigate the cause of RDS in full-term neonates by a retrospective case-control study. Study Design: Case-control study. Methods: Among the patients admitted to Bayi Children's Hospital between January 2008 and December 2010, a total of 205 full-term neonates with RDS were assigned to the study group, and 410 full-term neonates without RDS were assigned to the control group. Clinical information, including the presence or absence of ...

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Section: Discussionmentioning

confidence: 99%

High-risk Factors of Respiratory Distress Syndrome in Term Neonates: A Retrospective Case-control Study

2014

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“…PROM occurring before 37 weeks of gestation is known as preterm premature rupture of membranes (PPROM), while term PROM applies to PROM after 37 weeks of gestation. The incidence of PROM is in the range of 1%–10% worldwide . PROM could lead to several adverse outcomes for both mothers and babies, including respiratory distress syndrome, intraventricular hemorrhage, infection, and even death .…”

Section: Introductionmentioning

confidence: 99%

Gestational hypertension and pre‐eclampsia and risk of spontaneous premature rupture of membranes: A population‐based cohort study

Liu

Wang

Yang

et al. 2019

Intl J Gynecology & Obste

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Objective: To examine whether gestational hypertension and pre-eclampsia are associated with spontaneous premature rupture of membranes (PROM). Methods:A retrospective, population-based cohort study was conducted in Hebei, Zhejiang, and Jiangsu provinces in China from 1993 to 1995. After excluding women with missing data of exposure and outcome, history of chronic hypertension, multiple births, and babies with major birth defects and ambiguous sex, this study comprised 199 231 singleton live births. Logistic regression was used to evaluate the association, adjusting for potential confounders.Results: The incidence of PROM was 17.7% and 8.9% in women with gestational hypertension and pre-eclampsia, respectively, and 5.9% for the normotensive group.Compared with normotension, gestational hypertension was associated with an increase in the odds of PROM of 4.21 times (95% confidence interval [CI] 3.77-4.70), while pre-eclampsia had an increase of 2.27 times (95% CI 1.78-2.88). Additionally, women with hypertensive disorders of pregnancy had higher risks for term PROM (adjusted risk ratio [RR] 3.83, 95% CI 3.43-4.27) than preterm PROM (adjusted RR 3.10, 95% CI 2.18-4.41). Consistent results of the association were also observed in the sensitivity analyses. Conclusion:Gestational hypertension and pre-eclampsia were associated with an increased risk for PROM. Increased odds were observed for term PROM compared with preterm PROM. K E Y W O R D SChinese women; Cohort study; Gestational hypertension; Pre-eclampsia; Premature rupture of membranes; Preterm; Term Gestational hypertension 1589 (19.8) 3.72 (3.50-3.95) 4.28 (3.40-5.39) Pre-eclampsia 239 (8.9) 1.46 (1.27-1.67) 2.12 (1.28-3.50) Abbreviations: CI, confidence interval; RR, risk ratio; PROM, premature rupture of membranes. a Adjusted for maternal age, BMI, gestational week, sex of infants, parity, ethnicity, education, occupation, history of abortion, and history of cesarean delivery. | 201Liu ET AL.

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“…It occurs in 3% of pregnancies and is responsible for approximately one‐third of all preterm births [3]. Despite the many advances in perinatal care, PPROM remains a potentially serious complication with significant risks of maternal and fetal morbidity [3–6]; studies have shown that there is a strong association between PPROM and infection [7].…”

Section: Introductionmentioning

confidence: 99%

Antibiotic susceptibility pattern of genital tract bacteria in pregnant women with preterm premature rupture of membranes in a resource-limited setting

Eleje

Adinma

Ghasi

et al. 2014

International Journal of Gynecology & Obstetrics

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The Incidence Rate of Premature Rupture of Membranes and its Influence on Fetal-neonatal Health: A Report From Mainland China

Cited by 49 publications

References 16 publications

High-risk Factors of Respiratory Distress Syndrome in Term Neonates: A Retrospective Case-control Study

High-risk Factors of Respiratory Distress Syndrome in Term Neonates: A Retrospective Case-control Study

Gestational hypertension and pre‐eclampsia and risk of spontaneous premature rupture of membranes: A population‐based cohort study

Antibiotic susceptibility pattern of genital tract bacteria in pregnant women with preterm premature rupture of membranes in a resource-limited setting

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