Billions of tons of waste are generated annually, with the amount of waste rapidly increasing and its management expected to worsen. Qatar is a small and wealthy country in the Arabian Peninsula that is undergoing enormous economic and urban development. This study presents the results of a systematic literature review on waste management in Qatar and offers recommendations for system strengthening based on an analysis of the available evidence. The PRISMA guidelines were followed to review literature from the ProQuest and SCOPUS platforms, from which 82 unique publications were analyzed according to ten themes. The results draw upon diverse disciplinary and research focus areas related to waste management, ranging from the generation of value-added products from wastes to the role of religion in waste management awareness. The main recommendations emerging from the available evidence include the need for a holistic approach to address increasing waste generation, which must include diverse stakeholders such as government entities, researchers, and broad community representation for decision making as well as raising awareness for behavior change. Additionally, the main waste types, including construction, food, plastic, and electronic wastes, require specific attention since the cause of generation and type of management varies accordingly. The rise of interest in improving waste management, in particular to work toward meeting the targets of the Qatar National Vision and the National Development Strategy should bring about positive outcomes for strengthening waste management systems.