The increasing incidence of foetal echogenic congenital lung malformations: an observational study

Abstract

There was over a three-fold increase in the antenatally detected CLM in the Wessex region 1994-2012. Comparison with the antenatal detection of diaphragmatic hernia suggests that this is a true rise in incidence rather than an artefactual increase due to increased antenatal recognition secondary to improved ultrasound resolution and operator experience. These results have clinical and cost implications for practitioners of foetal medicine, neonatology and paediatric surgery services.

The natural history of prenatally diagnosed congenital cystic lung lesions: long-term follow-up of 119 cases

“…Routine fetal anomaly scanning, together with advances in ultrasonographic technology have resulted in an increase in the prenatal detection of congenital lung malformations (CLMs), with current prevalence estimated at 4.15 per 10 000 births 1. The CLM complex represents a heterogeneous group of abnormalities that include cystic pulmonary airway malformations (CPAMs), pulmonary sequestrations (PS), bronchogenic cysts, bronchial atresias and hybrid forms of these lesions.…”

Pediatric Pulmonology Year in Review 2018: Rare lung disease, neuromuscular disease, and diagnostic testing

“…Identification of congenital lung malformations (CLMs) has increased substantially in recent decades, although it is unclear if this is due to a true rise in incidence, or from more widespread use and improved sensitivity of prenatal ultrasound (US) . While it is widely accepted that CLMs causing hydrops, pneumothorax, or recurrent pneumonia require intervention, the optimal management of asymptomatic lesions is a divisive topic.…”

“…increased substantially in recent decades, although it is unclear if this is due to a true rise in incidence, or from more widespread use and improved sensitivity of prenatal ultrasound (US). 4,5 While it is widely accepted that CLMs causing hydrops, pneumothorax, or recurrent pneumonia require intervention, the optimal management of asymptomatic lesions is a divisive topic. The main argument in favor of early resection is to decrease the later risk of infection and malignancy within the lesions, risks that some contend are overstated.…”

Lung function, exercise tolerance, and physical growth of children with congenital lung malformations at 8 years of age

“…CLM are increasingly detected prenatally as a result of routine fetal anomaly scanning and improved ultrasound technology. The current estimated incidence is 4.15 per 10 000 births . Children with CLM who develop symptoms, either directly after birth or later in life, undergo surgery.…”

“…The current estimated incidence is 4.15 per 10 000 births. 2 Children with CLM who develop symptoms, either directly after birth or later in life, undergo surgery.…”