The Incremental Prognostic Value of the Incorporation of Myocardial Perfusion Assessment into Clinical Testing with Stress Echocardiography Study

Shah, Benoy N.; Gonzalez-Gonzalez, Ana M.; Drakopoulou, Maria; Chahal, Navtej; Bhattacharyya, Sanjeev; Li, Wei; Khattar, Rajdeep; Senior, Roxy

doi:10.1016/j.echo.2015.07.001

Cited by 21 publications

(5 citation statements)

References 20 publications

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“…A recent study, using myocardial contrast echocardiography (MCE) which assesses myocardial perfusion and wall motion simultaneously, showed excellent sensitivity for MCE (93%) for predicting abnormal FFR, but numbers were smaller and patients predominantly had single vessel disease (where sensitivity was 81% in the present study) (14). The higher sensitivity of MCE can be explained by the fact that perfusion abnormalities precede wall thickening abnormalities (19,20). Similar to the present study a large proportion of negative FFR patients, had positive MCE (57%) but unlike the present study hard outcomes were not examined (14).…”

Section: Diagnostic Performance Of Se Versus Ffrmentioning

confidence: 46%

Diagnostic Concordance and Clinical Outcomes in Patients Undergoing Fractional Flow Reserve and Stress Echocardiography for the Assessment of Coronary Stenosis of Intermediate Severity

Gurunathan

Ahmed

Vamvakidou

et al. 2018

Journal of the American Society of Echocardiography

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Section: Diagnostic Performance Of Se Versus Ffrmentioning

confidence: 46%

Diagnostic Concordance and Clinical Outcomes in Patients Undergoing Fractional Flow Reserve and Stress Echocardiography for the Assessment of Coronary Stenosis of Intermediate Severity

Gurunathan

Ahmed

Vamvakidou

et al. 2018

Journal of the American Society of Echocardiography

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“…160 A recent study also showed that when MCE was performed routinely during SE in the day-to-day clinical service where MCE was used in decision making provided improved prognostic outcome over wall motion. 159 The incremental prognostic value of MCE in SE was demonstrated in a recent meta-analysis. 172 Figure 9 Apical four-chamber view at rest (left) demonstrating normal myocardial perfusion at rest (5 s after myocardial contrast destruction).…”

Section: Myocardial Contrast Echocardiographymentioning

confidence: 96%

Clinical practice of contrast echocardiography: recommendation by the European Association of Cardiovascular Imaging (EACVI) 2017

Senior

Becher²,

Monaghan

et al. 2017

European Heart Journal - Cardiovascular Imaging

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118

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Contrast echocardiography is widely used in cardiology. It is applied to improve image quality, reader confidence and reproducibility both for assessing left ventricular (LV) structure and function at rest and for assessing global and regional function in stress echocardiography. The use of contrast in echocardiography has now extended beyond cardiac structure and function assessment to evaluation of perfusion both of the myocardium and of the intracardiac structures. Safety of contrast agents have now been addressed in large patient population and these studies clearly established its excellent safety profile. This document, based on clinical trials, randomized and multicentre studies and published clinical experience, has established clear recommendations for the use of contrast in various clinical conditions with evidence-based protocols.

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“…The incorporation of MCE into an exercise stress test is challenging but has been shown to be feasible with improvement of both left ventricular wall assessment and perfusion [23, 24]. It is known that a perfusion defect precedes a wall motion abnormality in the ischemic cascade.…”

Section: Clinical Utility Of Contrast Echocardiographymentioning

confidence: 99%

Contrast echocardiography in daily clinical practice

Eskandari

Monaghan

2017

Herz

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Ultrasound contrast agents have unique acoustic properties that enable them to enhance the cardiac blood flow and thus are used broadly in modern echocardiography laboratories for salvage of nondiagnostic studies, improving accuracy and reducing variability even in the presence of adequate image quality. Contrast echocardiography is also used as an adjunctive technique when unenhanced echocardiography falls short in the differentiation of cardiac structural abnormalities such as cardiac masses. Ultrasound contrast agents are pure intravascular tracers. Development of innovative ultrasound imaging techniques has led to myocardial perfusion imaging with contrast echocardiography. Although currently an off-label indication, it has been shown that perfusion imaging with contrast echocardiography adds incremental value to stress echocardiography in the detection of coronary artery disease. Moreover, it can be used for assessment of myocardial viability. In this paper we briefly discuss the basics of contrast echocardiography and its use in daily clinical practice.

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The Incremental Prognostic Value of the Incorporation of Myocardial Perfusion Assessment into Clinical Testing with Stress Echocardiography Study

Cited by 21 publications

References 20 publications

Diagnostic Concordance and Clinical Outcomes in Patients Undergoing Fractional Flow Reserve and Stress Echocardiography for the Assessment of Coronary Stenosis of Intermediate Severity

Diagnostic Concordance and Clinical Outcomes in Patients Undergoing Fractional Flow Reserve and Stress Echocardiography for the Assessment of Coronary Stenosis of Intermediate Severity

Clinical practice of contrast echocardiography: recommendation by the European Association of Cardiovascular Imaging (EACVI) 2017

Contrast echocardiography in daily clinical practice

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