The Index of Health-related Quality of Life (IHQL): a new tool for audit and cost-per-QALY analysis

Rosser, Rachel; Allison, Richard; Butler, Carole; Cottee, Michaela; Rabin, Rosalind; Selai, Caroline

doi:10.1007/978-94-011-2988-6_8

Cited by 7 publications

(6 citation statements)

References 3 publications

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“…Several evaluations report similar levels of reliability and evidence for validity between the SF-36 and EQ-5D [63,99], and between the SF-36 and NHP [60,73,99]. The SF-36 appears to be more responsive to change in health across lower levels of morbidity [63,64,73], but the EQ-5D [63,99] and NHP [72,73,101] may be more responsive where substantive changes in health are expected. Comparable levels of responsiveness have been reported between the COOP and SF-36 [35], and WONCA/COOP and NHP [72,101].…”

Section: Concurrent Evaluationsmentioning

confidence: 65%

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Quality of life in older people: A structured review of generic self-assessed health instruments

2005

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There is good evidence for reliability, validity and responsiveness for the SF-36, EQ-5D and NHP. There is more limited evidence for the COOP, SF-12 and SIP. The SF-36 is recommended where a detailed and broad ranging assessment of health is required, particularly in community dwelling older people with limited morbidity. The EQ-5D is recommended where a more succinct assessment is required, particularly where a substantial change in health is expected. Instrument content should be assessed for relevance before application. The concurrent evaluation of generic instruments in older people is recommended.

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Section: Concurrent Evaluationsmentioning

confidence: 65%

“…A scoring algorithm is used to generate an index score between 0 and 1. Alternatively, a five-level multi-dimensional classification across the three domains may be produced [12,64].…”

Section: Utility Measuresmentioning

confidence: 99%

Quality of life in older people: A structured review of generic self-assessed health instruments

2005

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“…The results of relevant studies are presented individually and the most plausible results used in further analyses. The Index of Health Related Quality of Life (IHQL) (5) is used to estimate benefits as Quality Adjusted Life Years (QALYs) where possible. QALY estimates are combined with cost data to provide an estimate of cost utility, allowing comparison of the value for money of the intervention in providing health gain.…”

Section: Methodsmentioning

confidence: 99%

Orlistat for the treatment of obesity: rapid review and cost‐effectiveness model

Foxcroft

Milne

2000

Obesity Reviews

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The aim of this study is to clarify the potential benefits, disbenefits and costs of Orlistat for the treatment of obesity. The method was a search for relevant systematic reviews and randomized controlled trials, in Medline, Pre-Medline, Embase and the Cochrane Library, using Orlistat and its synonyms. Identified trials were appraised using a standard appraisal checklist and trial data were extracted for use in cost-effectiveness modelling. Three large multicentre, randomized placebo controlled trials were included in the rapid review. On average, Orlistat results in obese people losing an additional 3-4% of their initial body weight over diet alone during a 2 year period. There was no strong evidence that this short-term weight loss would have a longer-term impact on morbidity and mortality. The cost utility of Orlistat treatment was estimated at around 46,000 Pounds per Quality Adjusted Life Year gained (extreme values sensitivity analysis 14,000 Pounds to 132,000 Pounds). This rapid review raises some important questions about the potential value of Orlistat in the treatment of obesity. Further research is needed, not only to clarify the longer-term impact of Orlistat treatment, but also to uncover the longer-term impact on mortality and morbidity from short-term weight loss.

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“…19 Later, Rosser separated distress into separate axes for physical discomfort and emotional distress and disability into dysfunction and dependency. 20 The wording, design and scoring system of howRu evolved over a two-year period through numerous iterations, using pilot studies, feedback from colleagues and members of the public and desk research including literature review, dictionaries and thesauri. The purpose was to use simple terms and descriptions, in order to reduce the risk of ambiguity and to ensure that as many people as possible could use the measure reliably and consistently without training or support.…”

Section: Descriptive Systemmentioning

confidence: 99%

Evaluation of a new short generic measure of health status: howRu

Benson¹,

Sizmur²,

Whatling³

et al. 2010

Journal of Innovation in Health Informatics

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Background Quality of life is paramount for patients and clinicians, but existing measures of health were not developed for routine use. Objectives This paper describes the development and testing of a new generic tool for measuring health related quality of life (HRQoL) with direct comparison to the SF-12 Health Survey. Methods The new tool (howRu) has four items (discomfort, distress, disability and dependence), rated using four levels (none, a little, quite a lot and extreme), providing 256 possible states (4

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The Index of Health-related Quality of Life (IHQL): a new tool for audit and cost-per-QALY analysis

Cited by 7 publications

References 3 publications

Quality of life in older people: A structured review of generic self-assessed health instruments

Quality of life in older people: A structured review of generic self-assessed health instruments

Orlistat for the treatment of obesity: rapid review and cost‐effectiveness model

Evaluation of a new short generic measure of health status: howRu

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