The Indo-Pacific (IP), the region covering the Indian Ocean and the Pacific Region, is concurrently shaping the posture of international affairs. As a littoral state and critical partner in the IP construct, Malaysia’s responses to this stance are inevitable due to its geostrategic location in the construct. This article argues that Malaysia’s posture vis-à-vis the IP as that of a ‘neutralist’. The discussion is divided into two sections. The first section describes weaknesses in the quadrilateral security dialogues (Quad) centrality using the features of regional security complex theory (RSCT). The second section discusses Malaysia’s neutrality vis-à-vis the IP construct. The article argues that, while opportunities can be seen in terms of strengthening the existing relations and tapping into new areas of partnership, Malaysia may face challenges in the form of marginalisation and entrapment. Apprehension is still prominent; therefore, the concept is in a ‘wait and see’ mode. The article concludes that the catalyst is found by drawing a more effective vision of the concept and is the key, particularly if the IP aspires to attract and appeal to Southeast Asian countries such as Malaysia.