The inducible form of heat shock protein 70 in the serum, colon and small intestine of the pig: Comparison to conventional stress markers

Heat shock protein 70 is upregulated in the intestine of intrauterine growth retardation piglets

“…Interestingly, we also found that the expression of Hsp70 is different among intestinal segments. A similar variation has been found in the induction of Hsp70 in pig after transportation (Sepponen and Pösö 2006). In the gastrointestinal tract of pigs, weaning has been shown to cause abnormal spatial-temporal patterns of Hsp70 expression (David et al 2002).…”

Gut epithelial inducible heat-shock proteins and their modulation by diet and the microbiota

“…30,38,58 By contrast, pigs exhibited substantial iHSP concentrations along both the small and large intestines. 45,[59][60][61][62][63] An increasing proximaldistal gradient of iHSPs along the small intestine has been described. 38,58 A proximal-distal gradient also exists along the large intestine of rodents, though with discrepancies between studies: decreasing vs increasing gradient.…”

Expression and distribution of heat shock proteins in the heart of transported pigs

“…Nevertheless, the precise function of the majority of these induced proteins remains unclear, although there is growing appreciation of the protective function of HSPs in the defensive mechanisms against tissue damage and their importance in many regulatory pathways. Furthermore, HSPs have become a focus of physiological research (Natelson et al 1988;Li et al 2006;Sepponen and Pösö 2006).…”