The influence of age, gender, refractive error, and optic disc size on the optic disc configuration in Japanese normal eyes

Abstract

ABSTRACT.Purpose: To investigate the influence of age, gender, refractive error, and optic disc size on optic disc configuration in Japanese normal eyes. Methods: Ninety-two eyes from 92 visually normal Japanese subjects (mean refractive error∫SD: ª1.26∫2.25 D, range ª8 D to π3 D) were examined using a confocal scanning laser tomograph, TopSS A . The following disc parameters were investigated: disc size, total or quadrant C/D area ratio and neuroretinal rim area, half-depth area, volume below, and average cup depth. Results: The disc diameter ( mean∫SD: 1.84∫0.16 mm) and disc size showed highly significant correlations with the C/D ratio (p∞0.001) and the neuroretinal rim area (p∞0.001). No other correlation was observed. Conclusion: These results indicate that the optic disc diameter and disc size have higher correlations with the optic disc configuration than age, gender, and refractive error in Japanese. These results are similar to those data reported for eyes of Caucasians or Afro Americans, and should be considered when optic discs are evaluated.

The morphology of the optic nerve head in the Singaporean Chinese population (the Tanjong Pagar study): part 1--optic nerve head morphology

“…Possible explanations for this observation might include variations in disc shape with age such as tilt and peripapillary atrophy but also planimetric issues such as increasing difficulty in identifying the temporal edge of the disc in older patients due to increased media opacity. Few studies report age-related changes of rim sectors 42. An increase in vertical cup/disc ratio with age was found.…”

“…No statistically significant relationship was found between rim area and age. Rim area has variously been described as reducing with age28 33 34 36 – 38 or remaining stable with age 3 17 – 19 25 31 39 – 41 42. In terms of rim sectors, the temporal sector area increased significantly with age, while the nasal sector decreased.…”

Optic Disk Size and Glaucoma

“…1,21,181,192 Using the CSLO, Bowd and colleagues demonstrated that optic disk area did not differ significantly between males and females (P > 0.05).21 This was supported by several other studies that measured disk size using confocal scanning laser opthalmoscopes. 1,42,109 In studies that have reported differences in disk size between genders, the differences were small. Population-based studies with a large number of subjects, such as the Baltimore Eye Survey 153,181 tended to report significantly larger disks in males compared to females.…”

Correlation Between Axial Length of Eyeball And Peripapillary Rnfl Thickness Measured By Oct in Myopes.

“…Several prior studies did not find a significant association between myopia and RNFL thickness [9,10,14,15]. These studies may have been limited by the poorer resolution of earlier generation OCT and confocal laser devices, and thus lower sensitivity.…”

“…Using the current generation Stratus OCT, Salchow et al [11]. found that RNFL thickness increased with increasing hyperopia (1.7 microns per diopter) in children (91% Hispanic, mean age 10 years, range [4][5][6][7][8][9][10][11][12][13][14][15][16][17]. Only five children with >4.00 diopters of myopia were assessed, which was too small for analysis.…”