The influence of bacterial selenium nanoparticles biosynthesized by Bacillus subtilus DA20 on blood constituents, growth performance, carcass traits, and gut microbiota of broiler chickens

Al-Quwaie, Diana A.

doi:10.1016/j.psj.2023.102848

Cited by 5 publications

(3 citation statements)

References 45 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Infection with E. tenella is followed by the inflammation of cecum cells and oxidative damage in chickens; while permitting an increase in the total count of bacteria, E. coli , total yeast, and molds, and reducing the lactic acid bacteria, these effects were reversed when added dietary selenium agreeing with Al-Quwaie (2023) , who found that the addition of selenium nanoparticles ( BSeNPs ) and elemental selenium ( Se ) significantly reduced the levels of total bacterial count ( TBC ), total yeast mold count ( TYMC ), E. coli , and Salmonella in comparison to the control group. However, the levels of lactic acid bacteria ( LAB ) were significantly increased.…”

Section: Discussionmentioning

confidence: 84%

Supplementing broiler diets with bacterial selenium nanoparticles enhancing performance, carcass traits, blood indices, antioxidant status, and caecal microbiota of Eimeria tenella-infected broiler chickens

Alsulami,

El-Saadony

2023

Poultry Science

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 84%

Supplementing broiler diets with bacterial selenium nanoparticles enhancing performance, carcass traits, blood indices, antioxidant status, and caecal microbiota of Eimeria tenella-infected broiler chickens

Alsulami,

El-Saadony

2023

Poultry Science

View full text Add to dashboard Cite

“…Selenium (Se) is one of the essential trace elements for maintaining normal physiological functions [15]. As a trace element with antioxidant effects, Se plays an indispensable role in the redox balance [16].…”

Section: Introductionmentioning

confidence: 99%

“…As a new form of Se supplement, selenium nanoparticles (SeNPs) can maximize the beneficial effects of Se because of its high surface activity and nanoscale effect [20]. Compared with inorganic selenium, SeNPs have a higher absorption rate, higher biological titer, and lower biological toxicity [15]. Moreover, SeNPs are cheaper and have a higher stability compared to organic selenium [21].…”

Section: Introductionmentioning

confidence: 99%

Biogenic Selenium Nanoparticles Synthesized with Alginate Oligosaccharides Alleviate Heat Stress-Induced Oxidative Damage to Organs in Broilers through Activating Nrf2-Mediated Anti-Oxidation and Anti-Ferroptosis Pathways

Ye,

Zhu,

Yang

et al. 2023

Antioxidants

View full text Add to dashboard Cite

Selenium (Se) is an essential trace element for maintaining health due to its ideal antioxidant properties. We previously prepared a new type of biogenic selenium nanoparticles based on alginate oligosaccharides (SeNPs-AOS), and this study aimed to investigate the protective effects of SeNPs-AOS (Se particle size = 80 nm, Se content = 8%) on organ health in broilers challenged with HS. A total of 192 21-day-old Arbor Acres broilers were randomly divided into four groups according to a 2 × 2 experimental design, including a thermoneutral zone group (TN, raised under 23 ± 1.5 °C); TN + SeNPs-AOS group (TN group supplemented 5 mg/kg SeNPS-AOS); HS group (HS, raised under 33 ± 2 °C for 10 h/day); and HS + SeNPs-AOS group (HS group supplemented 5 mg/kg SeNPS-AOS). There were six replicates in each group (eight broilers per replicate). The results showed that SeNPs-AOS improved the splenic histomorphology, enhanced the activity of catalase (CAT) and glutathione peroxidase (GSH-Px) of the spleen, as well as upregulating the splenic mRNA expression of antioxidant-related genes in broilers under HS. In addition, SeNPs-AOS reversed the pathological changes in bursa caused by HS increased the activity of GST, GSH-Px, and CAT and upregulated the mRNA expression of Nrf2 and antioxidant-related genes in the bursa of heat-stressed broilers. In addition, dietary SeNPs-AOS improved the hepatic damage, increased the activity of GSH-Px in the liver, and upregulated the mRNA expression of antioxidant-related genes while downregulating the Keap1 gene expression of the liver in broilers during HS. Moreover, dietary SeNPs-AOS upregulated the anti-ferroptosis-related genes expression of liver in broilers under HS. In conclusion, dietary SeNPs-AOS could relieve HS-induced oxidative damage to the spleen, bursa of Fabricius and liver in broilers by upregulating the Nrf2-mediated antioxidant gene expression and SeNPs-AOS could also upregulate the expression of hepatic Nrf2-related anti-ferroptosis genes in heat-stressed broilers. These findings are beneficial for the development of new nano-antioxidants in broilers.

show abstract

Dietary Supplementation of Microalgae and/or Nanominerals Mitigate the Negative Effects of Heat Stress in Growing Rabbits

Bashar,

Abdelnour,

El-Darawany

et al. 2023

Biol Trace Elem Res

View full text Add to dashboard Cite

Heat stress (HS) is one of the most significant environmental factors that result in fluctuations and shrinkage in rabbit growth, health, and overall productivity. This study aims to investigate the effects of dietary mineral nanoparticles (selenium or zinc) and/or Spirulina platensis (SP) independently and in combination on stressed growing rabbits. A total of 180 weaned growing New Zealand White rabbits were included in this study and randomly divided into six dietary treatments. Rabbits received a basal diet (control group; CON group) or fortified with SP (1 g/kg diet), selenium nanoparticles (SeNPs, 50 mg/kg diet), zinc nanoparticles (ZnNPs, 100 mg/kg diet), and a mixture of SP and SeNPs (SPSeNPs) or SP and ZnNPs (SPZnNPs) groups for 8 weeks during summer conditions. The obtained results demonstrated a significant increase in the final body weight and weight gain (p < 0.05). Additionally, the feed conversion ratio was improved during the periods from 6 to 14 weeks in the treated rabbits compared to those in the CON group. Dietary supplements considerably improved (p < 0.05) the blood hematology (WBCs, Hb, RBCs, and Hct) and some carcass traits (liver weights and edible giblets). All dietary supplements significantly decreased serum levels of total glycerides (p < 0.0001), AST (p = 0.0113), ALT (p = 0.0013), creatinine (p = 0.0009), and uric acid (p = 0.0035) compared to the CON group. All treated groups (except ZnNPs) had lower values of total bilirubin and indirect bilirubin in a dose-dependent way when compared to the CON group. The values of IgA, IgG, and superoxide dismutase were significantly improved (p < 0.05) in all treated rabbits compared to the CON group. Compared with the CON group, the levels of T3 (p < 0.05) were significantly increased in all treated growing rabbits (except for the ZnNP group), while the serum cortisol, interferon-gamma (IFN-γ), malondialdehyde, and protein carbonyl were significantly decreased in the treated groups (p < 0.05). Dietary supplements sustained the changes in hepatic, renal, and cardiac impairments induced by HS in growing rabbits. Adding SP (1 g/kg diet) or SeNPs (50 mg/kg diet) in the diet, either individually or in combination, improved growth performance, blood picture, and immunity-antioxidant responses in stressed rabbits. Overall, these feed additives (SP, SeNPs, or their mixture) can be applied as an effective nutritional tool to reduce negative impacts of summer stress conditions, thereby maintaining the health status and improving the heat tolerance in growing rabbits.

show abstract

The influence of bacterial selenium nanoparticles biosynthesized by Bacillus subtilus DA20 on blood constituents, growth performance, carcass traits, and gut microbiota of broiler chickens

Cited by 5 publications

References 45 publications

Supplementing broiler diets with bacterial selenium nanoparticles enhancing performance, carcass traits, blood indices, antioxidant status, and caecal microbiota of Eimeria tenella-infected broiler chickens

Supplementing broiler diets with bacterial selenium nanoparticles enhancing performance, carcass traits, blood indices, antioxidant status, and caecal microbiota of Eimeria tenella-infected broiler chickens

Biogenic Selenium Nanoparticles Synthesized with Alginate Oligosaccharides Alleviate Heat Stress-Induced Oxidative Damage to Organs in Broilers through Activating Nrf2-Mediated Anti-Oxidation and Anti-Ferroptosis Pathways

Dietary Supplementation of Microalgae and/or Nanominerals Mitigate the Negative Effects of Heat Stress in Growing Rabbits

Contact Info

Product

Resources

About