Buildings are significant consumers of energy and producer of greenhouse gases worldwide, and serious efforts have been put into designing energy-efficient buildings. Significant technological advances have been achieved in developed countries; however, advances have rarely been adopted in developing countries like Afghanistan. Such trends emerge from the lack of research in designing energy-efficient buildings to local conditions, practices and materials. This research focused on building energy modelling and simulation to evaluate the energy performance impact of different shading and orientation. The research design follows a case study over an actual seven-storey multi-apartment residential building in the city of Mazar-I-Sharif, Afghanistan, using primary field data and dynamic simulation. Findings demonstrated that neighbouring structures have a positive correlation with a cooling demand. Meanwhile, south is the optimal orientation to face the building's glazed façade, saving up to 7.4% of cooling and 9.7% of heating energy. Moreover, movable shading devices installed on the building's openings in the summer season reduce the building energy load up to 19%, with a total energy cost reduction of AFN. 188,448 ($2447.37 US) annually. The study underlines the vast research scope in customizing building designs to Afghanistan's climatic conditions and other developing countries, thus contributing to buildings’ sustainability.