The influence of climate change on skin cancer incidence – A review of the evidence

Parker, Eva Rawlings

doi:10.1016/j.ijwd.2020.07.003

Cited by 104 publications

(62 citation statements)

References 97 publications

(58 reference statements)

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“…As discussed in detail earlier in this journal ( Parker, 2020 ), pollution is associated with an increased risk for skin cancer ( Baudouin et al, 2002 ). The “pollutants” that react most specifically with the skin are UV radiation, PAHs (eg, benzo[ a ]pyrene), VOCs (eg, benzene), heavy metals, and O3.…”

Section: Skin Disorders Associated With Pollutionmentioning

confidence: 90%

Air pollution and skin disorders

Roberts¹

2021

International Journal of Women's Dermatology

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Air pollution is being shown to play an increasing causation role in our most common skin diseases. Acne, hyperpigmentation, atopic dermatitis, and psoriasis have been shown to be influenced by air pollution. It is important for pollution to be added as a risk factor for these skin disorders, and thus we must discuss mitigating its negative affects with patients. Air pollution is the contamination of outdoor (ambient) and indoor (household) environments by any chemical, physical, or biological agent that modifies the natural characteristics of the atmosphere. Nearly all (90%) of the world’s population experience daily pollution. In 2019, air pollution was considered by the World Health Organization to be the biggest environmental health risk to humans, responsible for killing more than 7 million people prematurely every year. Preliminary studies link air pollution to COVID-19 deaths, as there were high death tolls in some of the most globally polluted areas. Air pollution affects many organ systems such as cardiovascular, pulmonary, central nervous, reproductive, and integumentary systems. In this study, we detail the current evidence linking specific skin and health disorders to air pollution.

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Section: Skin Disorders Associated With Pollutionmentioning

confidence: 90%

Air pollution and skin disorders

Roberts¹

2021

International Journal of Women's Dermatology

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“…An emerging issue that is related to climate change would be mass migration caused by displacement due to climate change induced natural disasters. These migrations have various dermatology implications as more globally vulnerable populations are generally the ones Studies find that the incident rates of skin cancer have increased alarmingly throughout the latter half of the mid-20 th century evidently related to stratospheric ozone depletion [9] as well as other issues brought on by climate change. The stratospheric ozone is vital regarding skin health and outside exposure as it serves as a filter for ultraviolet radiation.…”

Section: Mass Migration and Infectious Cutaneous Diseasementioning

confidence: 99%

“…In the United States alone there has been a massive increase in the number of cases of nonmelanoma skin carcinoma since 1975. Figure 1 shows this rising trend of new melanoma cases from 1975 to 2016 [9]. This data was collected using programs SEER 9 which include diagnosed cases from 1975 through the though the pace of this change is frequently debated.…”

Section: Mass Migration and Infectious Cutaneous Diseasementioning

confidence: 99%

“…Skin cancer can develop quickly and can remain undetected due to the carcinogenic nature of ultraviolet rays. Research found that ultraviolet radiation has been determined to be a complete carcinogen due to its role as a mutagen and its ability to cause tumor formation without needing any additional inducement [9]. A 2011 study that was presented by the Australian based Cancer Council Victoria estimated that 450,000 of Australians get skin cancer every year.…”

Section: Mass Migration and Infectious Cutaneous Diseasementioning

confidence: 99%

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Climate Change and the Impact on Dermatology

Abigail¹

2021

J Dermatol Res Ther

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Climate change has a very real impact on your skin, adding an extra hurdle in the field of dermatology. Research shows a link between climate change and issues ranging from pediatric skin health to even causing an increase in skin cancer. There has been a large increase in climate inaction due to the Covid-19 pandemic. We will review this research as well as the implications of a deteriorating climate change on our own skin health and consider how the rise in climate inaction will further impact skin health. Review ARTicleCheck for updates search. Issues such as fighting climate change were put on the back burner. While there have been improvements regarding short-term environmental issues, such as limited movement increasing air quality, long-term effects will worsen due to the lower funding towards research. Due to funding being redirected to Covid-19 relief there has been an increased rate of inaction with this global issue.Climate change can present in many ways. Climate change is frequently defined as long term changes in average weather patterns of a given geography. These changes can result in colder or warmer than average temperatures, unusual weather events, pollution, and air quality fluctuations. All these factors can play a significant role in skin health. Effects of climate change on skin health can vary due to other factors such as age and health status but can also be impacted by social factors such as socioeconomic status and geography.Our skin is our first line of defense and protects our entire body. The more pollution that there is in the air the more at risk we are to poor skin health and a higher rate of skin conditions caused or worsened by external factors. External factors have a huge influence on skin health and can cause new conditions as well as aggravate preexisting conditions. For example, warmer temperatures -especially with higher levels of humidity -have an impact on the activity of infectious microorganisms as well as their vectors which causes an increase in infectious diseases including many that are dermatology based [1]. While this is something that will have an impact on all individuals, there are specific demographics that are at a higher risk.

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“…Chronic unprotected exposure to the sun is associated with the development of skin disorders such as altered immunity, photoaging, and cancer [1,2]. In the latter case, epidemiological surveillance has shown alarming trends [3,4] that claim more attention to photoprotective behavior. One of the primary photoprotection strategies is the application of sunscreen and/or sunblock [5].…”

Section: Introductionmentioning

confidence: 99%

Cliona varians-Derived Actinomycetes as Bioresources of Photoprotection-Related Bioactive End-Products

et al. 2021

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Sunscreen and sunblock are crucial skincare products to prevent photoaging and photocarcinogenesis through the addition of chemical filters to absorb or block ultraviolet (UV) radiation. However, several sunscreen and sunblock ingredients, mostly UV filters, have been associated with human and environmental safety concerns. Therefore, the exploration and discovery of promising novel sources of efficient and safer compounds with photoprotection-related activities are currently required. Marine invertebrates, particularly their associated microbiota, are promising providers of specialized metabolites with valuable biotechnological applications. Nevertheless, despite Actinobacteria members being a well-known source of bioactive metabolites, their photoprotective potential has been poorly explored so far. Hence, a set of methanolic extracts obtained from Cliona varians-derived actinomycetes was screened regarding their antioxidant and UV-absorbing capacities (i.e., photoprotection-related activities). The active extract-producing strains were identified and classified within genera Streptomyces, Micrococcus, Gordonia, and Promicromonospora. This is the first report of the isolation of these microorganisms from C. varians (an ecologically important Caribbean coral reef-boring sponge). The in vitro cytotoxicity on dermal fibroblasts of oxybenzone and the selected active extracts revealed that oxybenzone exerted a cytotoxic effect, whereas no cytotoxic effect of test extracts was observed. Accordingly, the most active (SPFi > 5, radical scavenging > 50%) and nontoxic (cell viability > 75%) extracts were obtained from Streptomyces strains. Finally, LC-MS-based characterization suggested a broad chemical space within the test strains and agreed with the reported streptomycetes’ chemodiversity. The respective metabolite profiling exposed a strain-specific metabolite occurrence, leading to the recognition of potential hits. These findings suggest that marine Streptomyces produce photoprotectants ought to be further explored in skincare applications.

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The influence of climate change on skin cancer incidence – A review of the evidence

Cited by 104 publications

References 97 publications

Air pollution and skin disorders

Air pollution and skin disorders

Climate Change and the Impact on Dermatology

Cliona varians-Derived Actinomycetes as Bioresources of Photoprotection-Related Bioactive End-Products

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