The influence of clusters in biomedical research: An example in cardiology

Lama, José M. de la

doi:10.1057/palgrave.jmm.5050045

Cited by 1 publication

(1 citation statement)

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“…In a 2006 study, comparing the published clinical trials of two drug-eluting stents between 2001 -2005 (Cypher, Cordis and Taxus, Boston Scientifi c), the author observed that the fi rst product to reach market generated more publications (188 versus 106) and higher-' quality ' publications (average quality score for study of 11 251 versus 7460) compared with the second product. 3 The introduction of new products is one of the main ways for medical device companies to increase sales. In fact, one of the key factors to sustain innovation is to maintain investment in R & D. According to Foray et al , investment in R & D is directly related, at company level, to a higher market capitalization and a higher sales growth.…”

Section: Original Articlementioning

confidence: 99%

Alternative market entry strategies for medical device products. How to develop relevant data when clinical information is lacking

Lama¹,

González²,

Marco³

2010

J Med Market

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The introduction of new products in the medical devices market is a critical activity. However, launches are not always accompanied by clinical or economic evidence to support the products' use, and, as a consequence, a company's commercial strategy is sometimes hampered. Using a real-life example, we propose a methodology that can generate relevant information with a goal of increasing product penetration. The product is an antiseptic suture that could reduce the rate of surgical infection. Although preclinical data for the product are positive, generating efficacy data through high-quality, prospective, randomized clinical trials is a technically difficult task. This results in a lack of evidence to support the claim of surgical site infection reduction at the time of product launch. To address this, we designed two animal models replicating orthopedic surgery (knee replacement) and, in parallel, we prepared an economic analysis. Our results could be used to support commercial activities and to accelerate the product's introduction in the market. This methodology could also be used for other indications, under appropriate conditions.

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Section: Original Articlementioning

confidence: 99%