2021
DOI: 10.21203/rs.3.rs-256191/v1
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The influence of Conditioned Stimuli on [11C]-(+)-PHNO PET Binding in Tobacco Smokers after a One Week Abstinence

Abstract: Stimuli previously paired with drugs of dependence can produce cravings that are associated with increased dopamine (DA) levels in limbic and striatal brain areas. Positron Emission Tomography (PET) imaging with [11C]-(+)-PHNO allows for a sensitive measurement of changes in DA levels. The purpose of the present study was to investigate changes in DA levels, measured with PET imaging with [11C]-(+)-PHNO, in regions of interest in smokers who had maintained abstinence for 7-10 days. Participants (N=10) underwen… Show more

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