The Influence of Fasting and Various Diets on the Liver Injury Effected by Chloroform Anesthesia

Abstract

Delayed chloroform injury has been reported occasionally since about 1850, sometimes diagnosed correctly, often called a postoperation acidosis or toxemia of unknown etiology ; sometimes called acute yellow atrophy when necropsy material was available. Experimental From

The Effect of Various Diets on the Liver Damage Caused by Excess Cystine

“…It has been reported that high dietary fat enhances the deleterious effect of various hepatotoxins (7)(8)(9)(10)(11)(12) or may produce cirrhosis (19,20). The present studies indicate that certain fats such as lard and cod liver oil, when fed as 25 per cent of the diet, have some protective effect against liver damage caused by excess cystine, while butter does not.…”

“…Most of the reported studies state that protein (8)(9)(10)(11)(12) and yeast (14) are protective against certain liver poisons. In the present experiments, liver damage resulting from 10 per cent cystine in low fat diets was not influenced by 5 or 40 per cent casein or by 5 or 20 per cent brewer's yeast.…”

The Influence of the Foodstuffs Upon the Susceptibility of the Liver to Injury by Chloroform, and the Probable Mechanism of Their Action 12

“…This hypothesis would satisfactorily account for the reported failure to obtain protection from injury by chloroform when glucose is administered during the anesthesia (4).…”

“…Fasting also intensifies to a great degree the susceptibility of the hepatic cells to injury by chloroform, comparable to (4), or exceeding (5) that which results from a high fat intake.…”

Treatment of Cirrhosis of the Liver by a Nutritious Diet and Supplements Rich in Vitamin B Complex

“…It has been known that starvation renders the liver more vulnerable to injury by hepatotoxins (9). Lack of certain food factors contained in yeast are said to cause fatty changes in the liver (10) and impaired function (11).…”