The influence of folates metabolism genes on the course of asthma during pregnancy

Abstract

s. The Bronchial asthma (BA) is one of the most urgent problems of pulmonology, at the same time continuous increase in number of patients around the world is noted. Purpose of the research is to determine the influence of genetic polymorphisms of the folates metabolism on asthma course during pregnancy. We are examined 96 pregnant women with BA: from them at 33 patients-controlled BA, at 39-partially controllable, at 24-uncontrollable. At 47 patients have a mild current, at 43-moderate and at 6-a severe asthma the comparison group consisted of 26 pregnant women without bronchopulmonary pathology.