The Influence of IL-11 on Cardiac Fibrosis in Experimental Models: A Systematic Review
Yarlla Loyane Lira Braga,
José Rodrigues do Carmo Neto,
Pablo Igor Ribeiro Franco
et al.
Abstract:Fibrosis is one of the main factors that impair the function of many organs. In the heart, fibrosis leads to contractile dysfunction and arrhythmias, which are important in the development of heart failure. Interleukin (IL)-11 is regulated in various heart diseases and has recently been reported to be an important cytokine in fibrosis in this organ. However, this topic has been little explored, and many questions persist. Thus, this systematic review aimed to report on possible IL-11 therapies evaluated in rod… Show more
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