“…This contrasts with findings in man where ileal infusion of undigested fat inhibited intake in excess of the level of energy infused (Welch et al 1985), perhaps via activation of an 'ileal brake', a slowing ofdigesta transit through the small intestine and slowing of gastric emptying (Read, McFarlane, Kinsman, Bates, Blackhall, Farrar, Hall, Moss, Morris, O'Neill, Welch, Lee & Bloom, 1984;Welch et al 1985). An 'ileal brake' mechanism appears to be absent in the pig, for ileal infusion of undigested fat or fat digestion products accelerates rather than slows transit through the small intestine (Gregory, Rayner & Wenham, 1986). This might explain why no immediate inhibition of food intake was seen in the present study.…”