The Influence of Knee Pain Location on Symptoms, Functional Status, and Knee-related Quality of Life in Older Adults With Chronic Knee Pain

Farrokhi, Shawn; Chen, Yi Fan; Piva, Sara R.; Fitzgerald, G. Kelley; Jeong, Jong‐Hyeon; Kwoh, C. Kent

doi:10.1097/ajp.0000000000000291

Cited by 35 publications

(32 citation statements)

References 50 publications

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“…The incidence of osteoarthritis is increasing with the increasing global ageing population; it is projected that the prevalence of osteoarthritis will increase from approximately 10% of people aged 60 years or older to 40% over the next 20 years . Osteoarthritis is associated with joint pain and stiffness, reduced balance, impeded mobility and loss of functional independence . These factors have all been previously demonstrated to be risk factors for falls in cohorts of older people …”

Section: Introductionmentioning

confidence: 99%

Is there an increased risk of falls and fractures in people with early diagnosed hip and knee osteoarthritis? Data from the Osteoarthritis Initiative

Smith

Higson²,

Pearson

et al. 2016

Int J of Rheum Dis

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Section: Introductionmentioning

confidence: 99%

Is there an increased risk of falls and fractures in people with early diagnosed hip and knee osteoarthritis? Data from the Osteoarthritis Initiative

Smith

Higson²,

Pearson

et al. 2016

Int J of Rheum Dis

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“…Osteoarthritis is the result of degeneration, thinning and even denudation of cartilage, which leads to pain and limitation of function. 18 Currently, the only effective solution Journal of Orthopaedic Surgery 28 (1) for osteoarthritis is joint replacement surgery. 19 However, it is an expensive and invasive procedure.…”

Section: Discussionmentioning

confidence: 99%

“…However, the predominant cause of chronic knee pain is cartilage wear and ulceration. 1 This is particularly pronounced over the patellofemoral and medial tibiofemoral joint.…”

Section: Introductionmentioning

confidence: 99%

Biological resurfacing of grade IV articular cartilage ulcers in knee joint with Hyalofast

Tan

Tho

2020

J Orthop Surg (Hong Kong)

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Introduction: Hyalofast grafting with microfracture is a new minimally invasive treatment method being proposed for joint cartilage defects. This study was done to measure the clinical efficacy of Hyalofast grafting after microfractures. Methods: Forty-six patients were assessed for knee function using knee injury and osteoarthritis outcome score (KOOS) after undergoing microfracture and Hyalofast grafting surgery. We further divided the 46 patients into a group of 10 patients who had no associated procedures done with the microfracture and Hyalofast grafting surgery. All patients had magnetic resonance imaging (MRI) of the affected knee pre-surgery and two patients had MRI done post-surgery. Due to another unrelated injury, we were also able to obtain further arthroscopic findings of another patient’s knee 18 months after microfracture and Hyalofast grafting. Results: There was a statistically significant improvement in all categories of the KOOS (symptoms, pain, daily living, sports and quality of life) compared between years 1, 2 and 3 against pre-surgery. For the subgroup of Hyalofast only, there was a statistically significant improvement in symptoms, pain and daily living categories of the KOOS compared between years 1, 2 and 3 against pre-surgery. Conclusions: Our study shows that Hyalofast grafting after microfracture is a viable alternative to treatment for patients with grade 4 cartilage ulcers.

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“…Patellofemoral (PF) osteoarthritis (OA) is highly prevalent and is associated with substantial pain, reduced function, and lower quality of life . Knee OA often begins at the patellofemoral joint, preceding multicompartment disease .…”

mentioning

confidence: 99%

“…Patellofemoral (PF) osteoarthritis (OA) is highly prevalent 1 and is associated with substantial pain, reduced function, and lower quality of life. [2][3][4][5] Knee OA often begins at the patellofemoral joint, preceding multicompartment disease. [6][7][8] An international consortium 9 in 2017 posited that knee malalignment (both patellofemoral and tibiofemoral) may increase patellofemoral joint stress, leading to OA.…”

mentioning

confidence: 99%

Alignment differs between patellofemoral osteoarthritis cases and matched controls: An upright 3D MRI study

Macri

d’Entremont

Crossley

et al. 2019

Journal Orthopaedic Research

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Patellofemoral (PF) osteoarthritis (OA) is a prevalent and clinically important knee OA subgroup. Malalignment may be an important risk factor for PF OA. However, little is known about alignment in PF OA, particularly in an upright, weightbearing environment. Using a vertically‐oriented open‐bore MR scanner, we evaluated 3D knee alignment in 15 PF OA cases and 15 individually matched asymptomatic controls. We imaged one knee per participant while they stood two‐legged at four flexion angles (0°, 15°, 30°, 45°), and also while they stood one‐legged at 30° knee flexion. We calculated 3D patellofemoral and tibiofemoral alignment. Using mixed effects models, four of the five patellofemoral measures differed by group. For key measures, PF OA patellae were 6.6° [95%CI 5.0, 8.2] more laterally tilted, 2.4 mm [1.3, 3.5] more laterally translated, and at least 3.7 mm [0.2, 7.2] more proximally translated compared to controls (more with knees flexed). Alignment did not differ between two‐legged stance and one‐legged stance in either group. Statement of Clinical Significance: Our study demonstrated significant and clinically relevant differences in alignment between PF OA cases and controls in upright standing and squatting positions. Our findings were similar to those in previous studies of PF OA using traditional MR scanners in supine positions, supporting the clinical usefulness of existing methods aimed at identifying individuals who may benefit from interventions designed to correct malalignment. © 2019 The Authors. Journal of Orthopaedic Research ® Published by Wiley Periodicals, Inc. on behalf of the Orthopaedic Research Society. 9999:1–9, 2019.

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The Influence of Knee Pain Location on Symptoms, Functional Status, and Knee-related Quality of Life in Older Adults With Chronic Knee Pain

Cited by 35 publications

References 50 publications

Is there an increased risk of falls and fractures in people with early diagnosed hip and knee osteoarthritis? Data from the Osteoarthritis Initiative

Is there an increased risk of falls and fractures in people with early diagnosed hip and knee osteoarthritis? Data from the Osteoarthritis Initiative

Biological resurfacing of grade IV articular cartilage ulcers in knee joint with Hyalofast

Alignment differs between patellofemoral osteoarthritis cases and matched controls: An upright 3D MRI study

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