The Influence of Lumbar Spinal Subtype on Lumbar Intervertebral Disc Degeneration in Young and Middle-Aged Adults

Torrie, P.A.G.; McKay, George; Byrne, Ryan M.; Morris, Stephen A.; Harding, Ian

doi:10.1016/j.jspd.2014.08.006

Cited by 16 publications

(19 citation statements)

References 46 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Morphological predictors of altered disc load outcomes were sagittal balance parameters in the thoracic spine and anatomic angles in the lumbar spine [19]. As expected, the Roussouly classification for categorizing the spinal alignments is inclusive and indicative, which considered most of the pelvic and spinal parameters [14].…”

Section: Discussionsupporting

confidence: 60%

“…Rafael et al [9], for example, found that Roussouly type II sagittal alignment is significantly associated with early disc degeneration at the L4-L5 level, compared with type IV. However, Torrie et al [14] proposed that lumbar sagittal subtypes were not statistically significantly correlated with LDD. Therefore, the relationship between spinal sagittal subtypes and LDD has not been clearly explained.…”

Section: Introductionmentioning

confidence: 99%

“…Several studies have evaluated the association between spinal sagittal morphology and LDD [9,14]. Rafael et al [9], for example, found that Roussouly type II sagittal alignment is significantly associated with early disc degeneration at the L4-L5 level, compared with type IV.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Different spinal subtypes with varying characteristics of lumbar disc degeneration at specific level with age: a study based on an asymptomatic population

Chen¹,

Li²,

Huang³

et al. 2020

J Orthop Surg Res

View full text Add to dashboard Cite

Background: The relationship between spinal sagittal subtypes and lumbar disc degeneration is unclear. Thus, we aimed to investigate the relationship between lumbar intervertebral disc degeneration and age in asymptomatic healthy individuals with different sagittal alignments. Methods: In this cross-sectional observational study, we examined 209 asymptomatic young and middle-aged volunteers (123 women and 86 men) who were divided into the following three groups according to age: groups A (20-30 years), B (31-40 years), and C (41-50 years). The volunteers underwent full-spine standing lateral radiography and magnetic resonance imaging (MRI, 3.0 T) of the lumbar spine. Based on panoramic radiography, two observers measured the spinopelvic parameters and classified the spine into Roussouly subtypes. The degree of disc degeneration was assessed based on T2-weighted images according to the Pfirrmann classification. Results: There was a statistically significant difference in the degree of degeneration of type I spine between groups B and C at L4-L5 (P < 0.03) and L5-S1 (P < 0.01) and between groups A and C at L1-L2 (P < 0.04) and L4-L5 (P < 0.01). The degeneration degree of type II spine at all levels were significantly different between groups A and C. No statistically significant difference was found between groups A and B in all subtypes except for type II spine at L1-L2 (P < 0.04). A significant difference was found at four levels between groups B and C in type III spine (P < 0.05) and between groups A and C. For type IV spine, there was a significant difference in the degree of degeneration at L4-L5 (P < 0.02) between groups A and C. Moreover, almost all single parameters were not strongly correlated with the degree of disc degeneration. Conclusion: The different spinal subtypes have characteristics of lumbar disc degeneration at specific levels with age. We considered that spinal classification could be used as a predictor of lumbar disc degeneration. Our data may be helpful to increase awareness of the relationship between spinal subtypes and lumbar disc degeneration.

show abstract

Section: Discussionsupporting

confidence: 60%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Different spinal subtypes with varying characteristics of lumbar disc degeneration at specific level with age: a study based on an asymptomatic population

Chen¹,

Li²,

Huang³

et al. 2020

J Orthop Surg Res

View full text Add to dashboard Cite

show abstract

“…Excluding extrinsic triggers of intervertebral disc degeneration, including physical activity ( 21 , 22 ), the parameters of lumbar spine sagittal alignment, including LL and PI, were considered to be strong predictors and serve a predisposing role in the pathogenesis of LDD diseases ( 12 , 23 ). SS, PI and LL have been observed to be different from type I to IV ( 5 , 23 ), thus, it was possible that different LSS (I-IV) may influence level-specific degeneration via specific biomechanical stressors. The Roussouly type II subtype is a flat lordosis that is characterized by mild thoracic and lumbar curvatures, with an SS of <35˚.…”

Section: Discussionmentioning

confidence: 99%

“…Lumbar disc degeneration (LDD), as the pathogenic cause of discogenic pain, has previously been correlated with lower back pain ( 3 ). The proportion of LDD still remains high in the asymptomatic population ( 4 , 5 ). The development of LDD has previously been described as a progressive process from mild to severe.…”

Section: Introductionmentioning

confidence: 99%

No evidence of a correlation between lumbar spinal subtypes and intervertebral disc degeneration among asymptomatic middle‑aged and aged patients

et al. 2020

View full text Add to dashboard Cite

The aim of the present study was to identify whether lumbar spinal subtypes (LSS) were associated with lumbar disc degeneration (LDD) among asymptomatic middle-aged and aged subjects. A cohort of 158 asymptomatic Chinese adults aged >40 years was recruited and 97 volunteers that met the inclusion criteria with complete information available were selected for inclusion. According to spinal morphology, volunteers were divided into four subtypes based on the classification of Roussouly. After baseline information was collected and spinopelvic parameters were measured, the data were compared among the four groups. According to the Pfirrmann classification, the degree of LDD was evaluated at each level on the MRI. For grades I-V, LDD at each level was effectively compared. Each of the four LSS from I to IV according to Roussouly classification from types I to IV were comprised of 25 (25.8%), 19 (19.6%), 38 (39.2%) and 15 (15.5%) of volunteers, respectively. Lumbar lordosis, sacral slope and pelvic incidence were significantly different among the four sub-types (P<0.001 for each), but no difference in pelvic tilt was observed (P=0.21). From types I to IV LSS, the proportion of disc degeneration was found to be 44, 52, 50 and 48%, respectively, which exhibited no statistically significant difference among LSS. No correlation between LSS and intervertebral disc degeneration was obtained among the asymptomatic middle-aged and aged subjects. The present study provides a reference for spinal surgery and indicated that additional risk factors should be assessed in the asymptomatic population of this age group, particularly in terms of differentially expressed genes.

show abstract

An in vivo study exploring correlations between early-to-moderate disc degeneration and flexion mobility in the lumbar spine

2020

View full text Add to dashboard Cite

Purpose Early disc degeneration (DD) has been thought to be associated with loss of spine stability. However, before this can be understood in relation to back pain, it is necessary to know the relationship between DD and intervertebral motion in people without pain. This study aimed to find out if early-to-moderate DD is associated with intervertebral motion in people without back pain. Methods Ten pain-free adults, aged 51–71, received recumbent and weight bearing MRI scans and quantitative fluoroscopy (QF) screenings during recumbent and upright lumbar flexion. Forty individual level and 10 composite (L2-S1) radiographic and MRI DD gradings were recorded and correlated with intervertebral flexion ROM, translation, laxity and motion sharing inequality and variability for both positions. Results Kinematic values were similar to previous control studies. DD was evidenced up to moderate levels by both radiographic and MRI grading. Disc height loss correlated slightly, but negatively with flexion during weight bearing flexion (R = − 0.356, p = 0.0.025). Composite MRI DD and T2 signal loss evidenced similar relationships (R = − 0.305, R = − 0.267) but did not reach statistical significance (p = 0.056, p = 0.096). No significant relationships between any other kinematic variables and DD were found. Conclusion This study found only small, indefinite associations between early-to-moderate DD and intervertebral motion in healthy controls. Motion sharing in the absence of pain was also not related to early DD, consistent with previous control studies. Further research is needed to investigate these relationships in patients.

show abstract

The Influence of Lumbar Spinal Subtype on Lumbar Intervertebral Disc Degeneration in Young and Middle-Aged Adults

Abstract: In this study, LSS was not statistically significantly correlated with LDD, nor was a high pelvic incidence protective against LDD.

Cited by 16 publications

References 46 publications

Different spinal subtypes with varying characteristics of lumbar disc degeneration at specific level with age: a study based on an asymptomatic population

Different spinal subtypes with varying characteristics of lumbar disc degeneration at specific level with age: a study based on an asymptomatic population

No evidence of a correlation between lumbar spinal subtypes and intervertebral disc degeneration among asymptomatic middle‑aged and aged patients

An in vivo study exploring correlations between early-to-moderate disc degeneration and flexion mobility in the lumbar spine

Contact Info

Product

Resources

About