The Influence of Magnetic Therapy and Naftalan Treatment on the Clinical Course of the Gastroesophageal Reflux Disease With the Concomitant Bronchial Asthma

Badalov, Nison; Efendieva, M T; Голубева, В В

doi:10.18821/1681-3456-2017-16-1-25-31

Cited by 4 publications

(2 citation statements)

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“…Involvement of adjacent systems and organs into a pathologic process determines diversity of clinical manifestation of a disease. Non-esophageal manifestations of GERD are commonly seen by cardiologists, ENT specialists, dentists [5][6][7][8][9]. Thus, GERD may rightly be called interdisciplinary problem.…”

Section: Introductionmentioning

confidence: 99%

“…Influence of low frequency magnetic therapy in a complex with local naphthalanum applications among GERD patients with сoncomitant bronchial asthma was investigated. Elaborated treatment course facilitated improvement of clinical manifestations of a disease, showed anti-inflammatory effect proved by decrease of eosinophils, fibrinogen, anti-inflammatory сytokines FHO-α and IL-1β in blood, normalization of physical features and microscopic сharacteristics of phlegm, improve of external breathing functional index [6]. Named studies reflected aspects related to clinical and functional state of esophagus and stomach; influence of physical factors on neurohumoral regulation of LES was not studied.…”

Section: Introductionmentioning

confidence: 99%

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Non-medicine Methods of Treatment of Gastroesophageal Reflux Disease

Efendiyeva¹

2021

IJG

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Few decades away a problem of throwing of acidic gastric content into an esophagus was reduced to the concept of reflux-esophagitis. In-depth study of pathogenesis of a disease resulted in "gastroesophageal reflux disease" (GERD) term which is acknowledged as leading disease of digestive system in terms of frequency and dangerous complications. GERD formation is determined by influence of numerous factors, however, it is generally accepted, that it is mainly related to insufficiency of lower esophageal sphincter (LES). Also, role of vasoactive intestinal peptide (VIP) in regulation of functional state of LES is determined. In spite of success in field of pharmacology, number of GERD patients has no downward trend which mainstreams search for non-medicine treatment methods. Physical factors affecting pathological processes by influencing regulatory processes are among these methods. Goal of this study is elaboration, scientific justification and clinical implementation of natural and preformed physical factors and acupuncture in treatment of patients with gastroesophageal reflux disease. Materials and Investigation methods: Randomized placebo-controlled study included 137 patients with gastroesophageal reflux disease, 63 (46%) men and 74 (54%) women, at the age of 18 to 65. Investigation included patients with no contraindications for physiotherapy. Patients with Barrett's esophagus, stricture of esophagus, esophagus ulcer have also been excluded from investigation. Patients were divided into 3 groups: Ist group -40 GERD patients, including high-frequency electromagnetic field effect and general iodine bromine bathes. II nd group -67 GERD patients passing acupuncture treatment course. Control group was comprised of 30 GERD patients, receiving placebo MEF therapy. Treatment was carried out without medicines. Therapeutic effectiveness of complex influence of microwave electromagnetic field therapy (MEF-therapy) applied to collar area alternated with general iodine-bromine bathes on clinical manifestations of GERD is determined. Treatment course contributed to reliable decrease of increased count of VIP -a neurotransmitter, regulating LES tonus. In term, it contributed to improve of functional state of LES, reliable decrease of reflux index, and, as a result, improvement of clinical and functional indicators. Estimation of clinical manifestations of a disease among patients of 2 nd group displayed positive dynamics of clinical and functional indicators. Round-clock pH-monitoring of stomach and esophageal content shows reliable decreaseof transitory relaxations of LES during single acupuncture procedure and increase of pH of gastric content. Acupuncture course also resulted in decrease of elevated VIP numbers.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%