1997
DOI: 10.1038/sj.ijir.3900257
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The influence of medication on erectile function

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Cited by 38 publications
(19 citation statements)
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“…14 Apart from potential disadvantageous effects of the drop in blood pressure following beta-blocker treatment the local balance of alpha and beta-adrenergic function may be pertubated and interfer with the vascular events during erection. 2,15,16 According to the results of our study educational, social as well as psychological factors might play the dominant role in the development of impotence as has been indicated in other studies dealing with quality of life in patients with coronary heart disease. 1,17 Further work is however needed to clarify the role of betablockers on the erectile function in different and larger populations.…”
Section: Discussionmentioning
confidence: 87%
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“…14 Apart from potential disadvantageous effects of the drop in blood pressure following beta-blocker treatment the local balance of alpha and beta-adrenergic function may be pertubated and interfer with the vascular events during erection. 2,15,16 According to the results of our study educational, social as well as psychological factors might play the dominant role in the development of impotence as has been indicated in other studies dealing with quality of life in patients with coronary heart disease. 1,17 Further work is however needed to clarify the role of betablockers on the erectile function in different and larger populations.…”
Section: Discussionmentioning
confidence: 87%
“…Beta-blockers seem to disturb the delicate balance between alpha-and beta-adrenergic nerve fibers. 2 However, it is surprising and unclear why not all or the majority of patients experience such side effects. In the following we report on a prospective, randomized and placebo controlled trial on the effect of beta-blockers on the sexual performance in men with coronary artery disease.…”
Section: Introductionmentioning
confidence: 99%
“…4 It has been suggested that this may be because of the change in balance between alpha and beta sympathetic influence, resulting in insufficient antagonism of alpha-1 vasoconstriction. 5 Many of these studies are biased by relatively heterogeneous groups of patients having organic or psychogenic (or both) predisposing factors in addition to drugrelated causes. We tried to minimize these confounding factors and investigated relatively young healthy men having mainly hypertension as a risk factor of vascular disease.…”
Section: Discussionmentioning
confidence: 99%
“…However, this association is sometimes difficult to prove and is probably often underreported. Drugs commonly reported to be associated with ED are cardiovascular drugs, histamine-2 receptor antagonists, hormones, anticholinergics, psychotropics, and certain cytotoxic medications (Meinhardt, Kropman, Vermeij, Nijeholt, & Zwartendijk, 1997). Lifestylerelated risk factors for ED include chronic alcoholism and chronic use of marijuana, codeine, meperidine, methadone, and heroin (Lewis, 2001).…”
Section: Medicationsmentioning
confidence: 99%