The Influence of Needle Size on Pain Perception in Patients Treated with Botulinum Toxin A Injections for Axillary Hyperhidrosis

Skiveren, Jette; Larsen, Heidi Nordahl; Kjaerby, Emmy; Larsen, Rune

doi:10.2340/00015555-0991

Cited by 19 publications

(10 citation statements)

References 15 publications

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“…Other studies 4 examined 2 larger (27- vs 30-gauge) needle sizes in the axilla and found no difference in discomfort. Similarly, when simple needle insertion without injection 5 into the thigh and abdomen was compared, the smaller needles were significantly less painful.…”

Section: Discussionmentioning

confidence: 91%

A Study to Examine the Effect of Needle Gauge on Pain Perception in Patients Receiving Treatment With Botulinum Toxin in 2 Different Anatomical Areas

Hollingsworth¹,

Brown

2020

Am J Cosmet Surg

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Botulinum toxin injection for treatment of rhytids is the commonest cosmetic intervention undertaken worldwide. It requires re-treatment at 3-month intervals for the effect to remain. Consequently, patient comfort is paramount in order for the procedure to remain acceptable. Intuitively, patients expect that smaller needles will be less painful, and this study examines the pain caused by needles of 2 gauges (31 and 32) when administering botulinum toxin in 2 anatomical areas. Patients were randomized into having the left or right side of their face treated with either a 31- or 32-gauge needle during botulinum toxin administration. Participants were asked to determine whether the left- or right-side treatment was most painful. The study was repeated in the glabellar and paraorbital regions. A total of 103 participants entered the study; 98 had the glabellar region treated and 76 the crow’s feet, and 72 patients had both regions treated. For the glabellar region, the smaller 32-gauge needle was significantly more painful than the larger 31-gauge needle ( P < .01). There was no difference in patient’s pain perception between gauges of needle when treating the crow’s feet area ( P = .9). The 31-gauge needles produce significantly less pain than smaller 32-gauge needles when treating the glabellar region with botulinum toxin, but not in the periorbital region. We propose that this is due to differences in fascial adherence between the 2 areas. Consequently, we would recommend administering botulinum toxin with a 31-gauge needle in all areas.

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Section: Discussionmentioning

confidence: 91%

A Study to Examine the Effect of Needle Gauge on Pain Perception in Patients Receiving Treatment With Botulinum Toxin in 2 Different Anatomical Areas

Hollingsworth¹,

Brown

2020

Am J Cosmet Surg

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“…The pressure depends on the needle caliber, for example, 27‐G needle was found to be more painful than 30‐G needle . In many of the studies, the needle sizes have been compared, the smaller bore needles resulted in less pain . However, the effect of syringe geometry remains another factor to be kept in consideration as well.…”

Section: Discussionmentioning

confidence: 99%

“…12 In many of the studies, the needle sizes have been compared, the smaller bore needles resulted in less pain. [13][14][15][16] However, the effect of syringe geometry remains another factor to be kept in consideration as well. The to reduce the injection force.…”

Section: Re Sultsmentioning

confidence: 99%

Effect of syringe size on severity of pain during local anesthesia administration

Malik¹

2019

J of Cosmetic Dermatology

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Objective To know the pain intensity experienced by the patients using the two different syringes keeping the needle size constant. Materials and Methods The split‐scalp, single‐blind study was conducted in patients after obtaining informed consent. On half of side, 1‐mL syringe with 30‐G needle was used whereas on the other half, 3‐mL syringe with 30‐G needle was used. On each side, about 10 mL of anesthetic solution (1% Xylocaine with epinephrine in 1:100 000 dilution) at the room temperature was injected. After the injections, the patients were asked to rate the pain experienced by using the Wong‐Baker Faces pain scale. The data were analyzed statistically using Mann‐Whitney’s U test. Results A total of 20 patients included 16 male and 4 females. The mean age in the males was 31.6 years and 28.8 years in females. The mean pain scale with 1‐mL syringe was 2.7 anteriorly and 2.45 posteriorly (P < 0.01), whereas the mean pain score with 3‐mL syringe was 4.5 anteriorly and 4.25 posteriorly (P < 0.01). The mean pain score with anterior injections in males was 2.5 vs 3.5 in females (1‐mL syringe) and 4.3 in males vs 5.5 in females (1‐mL syringe). Similarly, the average pain score with posterior injections was 2.4 in males vs 2.8 in females (1‐mL syringe) and 4.2 in males vs 4.5 in females (3‐mL syringe), respectively (P < 0.01). Conclusion The pain intensity is affected by syringe size.

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“…The pain scores recorded after the first five injections were significantly lower for the 30G needle than for the 27G needle. For this reason, smaller needles are preferable to improve patient comfort (Skiveren et al 2011).…”

Section: Injection Techniquementioning

confidence: 99%

Toxins for Hyperhidrosis in the Axillary Area

Almeida¹,

Montagner²

2016

Botulinum Toxins, Fillers and Related Substances

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The Influence of Needle Size on Pain Perception in Patients Treated with Botulinum Toxin A Injections for Axillary Hyperhidrosis

Cited by 19 publications

References 15 publications

A Study to Examine the Effect of Needle Gauge on Pain Perception in Patients Receiving Treatment With Botulinum Toxin in 2 Different Anatomical Areas

A Study to Examine the Effect of Needle Gauge on Pain Perception in Patients Receiving Treatment With Botulinum Toxin in 2 Different Anatomical Areas

Effect of syringe size on severity of pain during local anesthesia administration

Toxins for Hyperhidrosis in the Axillary Area

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