Cellulose nanocrystals (CNC) has been investigated for a potential new application, enhanced oil recovery (EOR), by performing core flooding experiments with CNC dispersed in low salinity brine (CNC-LS) in outcrop sandstone cores. Experiments on 100 % water saturated cores confirmed that most of the viscosity generating CNC particles were able to travel through the cores at temperatures ranging from 60, to 120 °C. Oil recovery experiments on crude oil saturated sandstone cores showed that when CNC-LS was used in tertiary mode, the ultimate oil recovery could be increased, both at 90 and 60 °C. During tertiary CNC-LS injection, the CNC particles increased fluctuations in differential pressure, an effect that can be linked to log jamming in pore throats leading to remobilisation of oil in the pore space. The results from this work indicate that CNC dispersed in low saline brine might have a certain potential for use in enhanced oil recovery.