1984
DOI: 10.1016/0007-0971(84)90118-9
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The influence of pretreatment with prostaglandin F2α on bronchial sensitivity to inhaled histamine and methacholine in normal subjects

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Cited by 22 publications
(2 citation statements)
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“…Initial studies in that area begin in the late 1970s and have started by looking at the combined effect of spasmogens on different measures of lung function in animals (45,46,57,99,102,112,131,152,180,181,192,208,209,224,244), as well as in humans (49,68,97,101,110,156,158,194,202,240). Apart from an interactive synergism at the level of ASM contraction, many other factors can account for these in vivo interactive synergisms.…”
Section: Interactive Synergisms Between Spasmogensmentioning
confidence: 99%
“…Initial studies in that area begin in the late 1970s and have started by looking at the combined effect of spasmogens on different measures of lung function in animals (45,46,57,99,102,112,131,152,180,181,192,208,209,224,244), as well as in humans (49,68,97,101,110,156,158,194,202,240). Apart from an interactive synergism at the level of ASM contraction, many other factors can account for these in vivo interactive synergisms.…”
Section: Interactive Synergisms Between Spasmogensmentioning
confidence: 99%
“…5 PGF 211 has been shown to sensitize normal airways to the ASTHMA MEDIATORS Drugs that block leukotriene synthesis may be useful in treating asthma. effects of histamine, 17 and it has been suggested that leukot:rienes may sensitize the bronchi to other mediators and lead to the hyperreactivity observed in asthmatics. 1 J.…”
Section: Prostaglandin D 2 Is the Most Abundant Cyclooxygenase Producmentioning
confidence: 99%