It is known that the physical properties of many engineering materials may be strongly affected by previous loading, in particular prior plastic deformation. Most obviously, work hardening will alter subsequent yielding behaviour. Plastic deformation may also preferentially align the material microstructure, resulting in anisotropy of subsequent behaviour and a change in material fracture resistance. When physical characterisation is undertaken by experimental testing it is, therefore, important to have some knowledge of the current state of the material. As a result, it is desirable to have methods of quantitatively evaluating the level of plastic deformation which specimen material may have experienced prior to testing. This paper presents the results of a feasibility study, using a ferritic reactor pressure vessel steel, into the use of diffractive methods for plastic strain evaluation. Using neutron diffraction, changes in diffraction peak width and anisotropy of peak response were correlated with plastic deformation in a tensile test. The relationships produced were then used to evaluate permanent deformation levels in large samples, representative of standard fracture toughness test specimens.