The influence of race on kidney graft survival

Dutra, Margarida Maria Dantas; Lopes, Antônio Alberto; Miranda, Eva Alves; Vinhaes, Antonio J.; Monte, N; Filho, José Siqueira de Araújo; Moura, Liberato Karaoglan de; Leite, Eneida Barreto; Barcía, Manuel; Lemaire, Denise Carneiro; Silva, I.C

doi:10.1016/s0041-1345(99)00650-8

Cited by 2 publications

(1 citation statement)

References 8 publications

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“…36 Although less comparable to Canada, Brazil has also been shown to have similar graft survival among black versus white patients in the recipients of living-donor kidneys. 37 There are a number of limitations to our study. The use of registry data has inherent shortcomings, including limited availability of clinical variables collected by the Canadian Renal Replacement Registry, the renal database we used for our analysis.…”

Section: Discussionmentioning

confidence: 94%

Similar Outcomes among Black and White Renal Allograft Recipients

Yeates¹,

Wiebe²,

Gill³

et al. 2009

Journal of the American Society of Nephrology

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Black renal transplant recipients experience shorter graft survival than white recipients, but no published data describe the graft outcomes among black Canadian recipients. Here, we analyzed data from the Canadian national renal replacement therapy registry, which included 20,243 incident dialysis patients (3% black, 97% white), 5036 of whom received a renal transplant during the study period. Black patients were significantly less likely to receive a renal transplant (deceased and living-donor combined) when compared with white patients (hazard ratio 0.59; 95% confidence interval 0.51 to 0.69; P Ͻ 0.0001). Among patients who underwent a renal transplant, there was no significant difference in the likelihood of graft failure between black and white patients, even after adjustment for comorbidities and socioeconomic status; black patients, however, had significantly lower posttransplantation mortality compared with white patients (hazard ratio 0.49; 95% confidence interval 0.28 to 0.88; P ϭ 0.02). In conclusion, graft outcomes between black and white Canadian renal transplant patients are similar. Because this differs from the experience reported from the United States, further direct comparisons between the two populations is warranted.

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Section: Discussionmentioning

confidence: 94%