The Influence of Radiation Therapy and Hyperbaric Oxygen Therapy on Osteoradionecrosis of the Jaw

Abstract

The object of this study was to estimate the influence of radiation therapy (RT) and hyperbaric oxygen therapy (HBO) on osteoradionecrosis of the jaw (ORNJ). This retrospective study included patients who were diagnosed with ORNJ from 1998 to 2012 (15 years) and who recieved a total dose of RT (Gy) for the duration of the study. The duration of ORNJ development and the healing period of ORNJ were examined. The mean dose of RT was 64.0 Gy. The mean healing period of ORNJ was 30.3 months in the continuous RT group, and 20.8 months in the pre-and post-operative irradiation group. The healing term for ORNJ with HBO was approximately the same as that without HBO. We concluded continuous RT may induce more severe ORNJ than pre-and postoperative RT, and that the effectiveness of HBO on ORNJ is suspicious.

Preliminary Study of the Efficacy of Conservative Treatment Using a Bite Plate for Condylar Neck Fracture of the Mandible

“…Some reports have suggested that conservative treatment may often cause complications such as abnormal occlusion, restricted jaw movement, traumatic arthritis, pseudoarthrosis, and fibrous or bony ankyloses [7][8][9][10] , while others have indicated that conservative treatment has led to better long-term follow-up results, and that it can contribute to improving functional occlusion and mastication despite leaving some malunion due to difficulty repairing small bone fracture for anatomical reasons [11][12][13][14][15] . With conventional conservative treatment, intermaxillary fixation is conducted for a fixed period of time to correct abnormal occlusion caused by the fracture, rest the fracture site, and encourage healing.…”