The influence of resistance training on adipokines in post-menopausal women: A brief review

Chapman-Lopez, Tomas; Wilburn, Dylan T.; Fletcher, Emma; Adair, Kathleen; Ismaeel, Ahmed; Heileson, Jeffery L.; Gallucci, Andrew; Funderburk, LesLee; Koutakis, Panagiotis; Forsse, Jeffrey S.

doi:10.1016/j.smhs.2022.09.001

Cited by 3 publications

(4 citation statements)

References 45 publications

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“…Sample size needed for this secondary analysis was determined to be a minimum of 16 subjects per group. This was performed using a 2-tail test with α = 0.05 and power set at 95% for anticipated differences in adiponectin concentrations (6). All subjects self-identified as reproductive, perimenopausal (PERI-M), or postmenopausal (POST-M).…”

Section: Methodsmentioning

confidence: 99%

“…Women who are postmenopause or are transitioning to postmenopause (perimenopause) commonly experience body mass gain as their estrogen levels drop (11,13,16). As older women progress into postmenopause and their estrogen levels decline along with physical activity, they will likely experience an excess accumulation of adipose tissue that increases the risk of developing obesity, inevitably leading to the secretion of various cytokines and inflammatory markers that may activate endocrine organs modulation of adipocyte secretion (5,6,7,12,14). This could potentially promote atypical changes in adipokines, such as adiponectin (decrease), leptin (increase), and visfatin (increase), which are associated with insulin resistance, inflammation, and other metabolic disorders (14,19,25,34,36).…”

Section: Introductionmentioning

confidence: 99%

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Effects of L-Leucine Supplementation and Resistance Training on Adipokine Markers in Untrained Perimenopausal and Postmenopausal Women

Chapman-Lopez,

Funderburk,

Heileson

et al. 2023

Journal of Strength and Conditioning Research

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Chapman-Lopez, TJ, Funderburk, LK, Heileson, JL, Wilburn, DT, Koutakis, P, Gallucci, AR, and Forsse, JS. Effects of L-leucine supplementation and resistance training on adipokine markers in untrained perimenopausal and postmenopausal women. J Strength Cond Res XX(X): 000–000, 2023—This study examined the effects of supplementing 5 g of leucine compared with a placebo during a 10-week resistance training program on body composition parameters and adipokine concentrations in untrained, perimenopausal and postmenopausal women. Thirty-five women were randomly assigned to 2 groups—leucine (LEU, n = 17) and placebo (PLC, n = 18)—in a double-blind, placebo-controlled trial. Each group consumed the supplement or placebo every day and completed a resistance training program for 10 weeks. Using 3-day food records, a diet was assessed before the intervention and after its cessation. Body composition was assessed preintervention and postintervention using dual-energy x-ray absorptiometry. Moreover, the concentrations of adipokines, such as adiponectin, visfatin, leptin, and monocyte chemoattractant protein-1 (MCP-1), were assessed preintervention and postintervention. Both groups showed an increase in visceral adipose tissue (VAT) area (p = 0.030) and fat-free mass (FFM; p = 0.023). There were significant group differences in concentrations of visfatin (p = 0.020) and leptin (p = 0.038) between the PLC and LEU groups. Visfatin displayed higher concentrations in the PLC group and leptin displayed higher concentrations in the LEU group. In addition, there were significant decreases in adiponectin concentrations for both groups (LEU: 652 ± 513 to 292 ± 447 pg·ml−1; PLC: 584 ± 572 to 245 ± 356 pg·ml−1, p = 0.002) and MCP-1 only decreased in the PLC group (253 ± 119 to 206 ± 106 pg·ml−1, p = 0.004). There were significant decreases in adiponectin concentrations in both groups and a decrease in MCP-1 concentrations in the PLC group. These decreases may be due to both adipokines possible relationship with VAT area. However, it is not known whether leucine has underlying properties that hinder changes in MCP-1 concentrations.

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Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Effects of L-Leucine Supplementation and Resistance Training on Adipokine Markers in Untrained Perimenopausal and Postmenopausal Women

Chapman-Lopez,

Funderburk,

Heileson

et al. 2023

Journal of Strength and Conditioning Research

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“…This likely could be due to the loss of fat mass the participants experienced, which has previously been shown to have a relationship with leptin concentrations [9,24]. However, while it is generally hypothesized that an increase in adipokines is associated with the increase of adipose tissue that an individual carries in their body, it is still unclear if there are any acute changes from single bouts of aerobic exercise training in various clinical populations [17,25,26].…”

Section: Introductionmentioning

confidence: 99%

“…Various therapeutic interventions (e.g., physical activity, resistance training (RT), aerobic exercise (AE), and nutrition) have been examined to identify a purposeful way to reduce the harmful effects of an over-production of pro-and anti-inflammatory adipokines in various clinical populations [17][18][19][20]. While the literature is still limited, some articles have acknowledged that exercise (both RT and AE) may be a powerful adipokine mediator in overweight and obese individuals suffering from excess adipose tissue [18,21,22].…”

Section: Introductionmentioning

confidence: 99%

The Effects of Acute Bouts of Aerobic Exercise on Adipokine Concentrations in Individuals with Moderate Stages of Chronic Kidney Disease

Chapman-Lopez,

Taylor,

Torres

et al. 2023

Physiologia

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This study examined the effects of two different acute bouts of treadmill running (e.g., steady-state moderate-intensity exercise (SSE) and high-intensity interval exercise (HIIE)) on adipokine (e.g., adiponectin, leptin, and omentin) concentrations in individuals with moderate stages of chronic kidney disease (CKD). Fourteen participants (8 females and 6 males) (age 58.7 ± 9.7, height (cm) 168.5 ± 9.7, weight (kg) 83.5 ± 18.2) were classified as having moderate stages of CKD (stages G3a and G3b; estimated glomerular filtration rate (eGFR) between 59 and 30 mL/min/1.73 m2). Participants completed 30 min of either SSE at 65% oxygen consumption reserve (VO2R) or HIIE for 3 min at a 90% VO2R separated by 2 min of slow walking (20% VO2R) in a randomized, crossover design on a treadmill. Venous blood samples were obtained at baseline, 1 h, and 24 h post exercise. Data were analyzed using a two by three repeated measures ANOVA (p < 0.05). There were no significant differences in adiponectin (p < 0.353), leptin (p < 0.084), and omentin (p < 0.235) concentrations between SSE and HIIE. Similarly, no significant differences were seen between the sampled time points for either aerobic exercise condition. In conclusion, this study demonstrated there were no changes in adiponectin, leptin, or omentin concentrations when performing an acute bout of HIIE or SSE for 30 min, at 1 or 24 h post exercise. Future studies should seek to either increase the duration of the exercise bout or identify different adipokines to examine for patients experiencing moderate stages of CKD.

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Jazz dancing for improving cardiorespiratory fitness, body composition, muscle strength, and sleep quality in postmenopausal women: a randomized clinical trial with 6- and 12-month follow-ups

Bocchi Martins,

Fausto,

Sonza

et al. 2025

Menopause

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Objective The aim of the study was to analyze the effects of 16 weeks of Jazz Dance training compared to a control group in postmenopausal women, postintervention, and at the 6- and 12-month follow-ups, on cardiorespiratory fitness, body composition, muscle strength, and sleep quality. Methods Two-arm randomized clinical trial with a total of 47 women (jazz dance intervention group [JDIG] [n = 23] and control group (CG) [n = 24]) with a mean age of 53.41 ± 2.8 y. Data collection was carried out at four times, baseline, postintervention, and 6- and 12-month follow-ups using the 6-minute walk test (cardiorespiratory fitness); bioimpedance (body composition); isokinetic dynamometry (muscle strength); and the Pittsburgh Sleep Quality Index (sleep quality). Results In the intention-to-treat analysis, the results showed positive differences for the JDIG in cardiorespiratory fitness at all time points (P = 0.034) and in the group x time interaction (P = <0.001). Lower limb muscle strength showed differences from baseline to postintervention and from baseline to the 12-month follow-up for the concentric force ratio (P = 0.021; P = 0.009). However, for peak extension and flexion, the results were not positive for the JDIG. There was a short-term improvement in sleep duration for the JDIG (P = 0.001) and significant intergroup differences in subjective sleep quality, where the JDIG showed better results compared to the CG (P = 0.041). Conclusions Jazz Dance is effective for improving cardiorespiratory fitness (in the short, medium, and long term) and sleep quality (in the short and medium term); however, it does not seem to have presented sufficient intensity and duration for facilitating changes in body composition or increasing lower limb muscle strength in postmenopausal women.

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The influence of resistance training on adipokines in post-menopausal women: A brief review

Cited by 3 publications

References 45 publications

Effects of L-Leucine Supplementation and Resistance Training on Adipokine Markers in Untrained Perimenopausal and Postmenopausal Women

Effects of L-Leucine Supplementation and Resistance Training on Adipokine Markers in Untrained Perimenopausal and Postmenopausal Women

The Effects of Acute Bouts of Aerobic Exercise on Adipokine Concentrations in Individuals with Moderate Stages of Chronic Kidney Disease

Jazz dancing for improving cardiorespiratory fitness, body composition, muscle strength, and sleep quality in postmenopausal women: a randomized clinical trial with 6- and 12-month follow-ups

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