The influence of selected ingredients of dietary supplements on skin condition

Szyszkowska, Barbara; Łepecka–Klusek, Celina; Kozłowicz, Katarzyna; Jazienicka, Iwona; Krasowska, Dorota

doi:10.5114/pdia.2014.40919

Cited by 34 publications

(27 citation statements)

References 28 publications

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“…Moreover, Table 2 showed that high amount of hydroxyproline and total protein extracted from granulation tissue of healed excised wound at the end of the study indicate a better wound contraction due to the increase of collagen formation and increase the amount of protein by pomelo peel extract PPE treated groups which was significantly different from that of both diabetic control and normal control groups, these results were comparable to other previous studies for wound healing. 27,3132 (Erdinc K. et al 2010, Szyszkowska B et al 2014) in their study pomelo content of flavonoids, carotenoids and vitamin C, enhances the epithelial cells migration, proliferation and stimulate collagen synthesis. 3435 The increase in the hydroxyproline and total protein content are indicators of new tissues generation.…”

Section: Discussionmentioning

confidence: 98%

The Role of Pomelo Peel Extract for Experimentally Induced Wound in Diabetic Rats

Ahmad¹,

Khalifa²,

Abudayeh³

2018

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Introduction:Delayed wound healing is a chronic complication in diabetic patients than in healthy individuals. Pomelo belongs to the genus Citrus of the family Rutaceae, an important fruit with great benefits for humans in the world. Previous studies showed that pomelo peels contain an abundant bioactive compound, which may promote wound healing in experimental animals. Aim: The current study was carried to prepare optimized extraction of pomelo peels using different experimental conditions and investigate the possible healing effect of oral treatment with pomelo peel extract (PPE) on induced excision skin wound in diabetic rats. Materials and Methods: This study was done on rats divided into five groups each of 8 rats (two treatment groups given PPE (400 and 600) mg/kg by oral gavage compared to two control groups and standard plant for wound healing). Diabetes was induced by intraperitoneal injection of a single dose of Streptozotocin (STZ) 65 mg\kg body weight. After diabetes induction, full thickness excision wound was made in rats, and the study continued for 3 weeks. Results: This study showed significant reduction in blood glucose and both percentage and time to wound closure in the treated groups, also a significant increase in hydroxyproline and total protein content of the healed wound tissue in the treated groups compared with control groups and comparable to standard plant extract treated groups. Conclusion: Experimental data proposed that oral administration of pomelo peel extract rich in vitamins and flavonoids has a good therapeutic potential in the treatment of complicated wounds in diabetes.

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Section: Discussionmentioning

confidence: 98%

The Role of Pomelo Peel Extract for Experimentally Induced Wound in Diabetic Rats

Ahmad¹,

Khalifa²,

Abudayeh³

2018

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“…Androgens stimulate the production of sebum, growth of the sebaceous glands and hyperkeratinization. Recent studies have shown that diet could play a role in the pathogenesis of acne [ 3 , 4 ]. It has also been shown that a low glycemic index (GI) diet induced an improvement in acne severity and a parallel improvement in insulin sensitivity in young males with acne vulgaris.…”

Section: Introductionmentioning

confidence: 99%

Original paper Insulin resistance in severe acne vulgaris

Emiroğlu¹,

Cengiz²,

Kemeriz³

2015

pdia

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IntroductionAcne vulgaris is a pilosebaceous gland disease that usually affects people from puberty to young adulthood. It is seen especially on the face, neck, trunk and arms. Its severity differs from patient to patient and its pathogenesis is multifactorial. The main pathogenic factors of acne are high sebaceous gland secretion, follicular hyperproliferation, high androgen effects, propionibacterium acnes colonization and inflammation. Diet is always thought a probable reason for acne and many studies are done about acne and diet.AimTo determine the effect of insulin resistance in severe acne vulgaris.Material and methodsTwo hundred and forty-three acne vulgaris patients and 156 healthy controls were enrolled into the study. The blood levels of insulin and glucose were measured. Homeostasis Model Assessment (HOMA) Index was calculated. The values were compared with the control group.ResultsAll of the patients were in the severe acne group according to their scores on the global acne scoring scale. While fasting blood glucose levels were not different between the groups (p > 0.05, 82.91 ±9.76 vs. 80.26 ±8.33), the fasting insulin levels were significantly higher in the patient group than in the control group (p < 0.001, 14.01 ±11.94 vs. 9.12 ±3.53). Additionally, there was a highly significant difference between the patient and control groups in terms of HOMA values (p < 0.001, 2.87 ±2.56 vs. 1.63 ±0.65).ConclusionsThese results suggest that insulin resistance may have a role in the pathogenesis of acne.

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“…It is of crutial importance to protect skin from negative factors like ultraviolet radiation, various chemicals, tobacco smoke, infections, as well as make available all the necessary nutrients in the diet, and appropriate care. In order to provide for normal functioning of the skin it is necessary to incorporate various foods of animal or plant origin, 18 which contain vitamins, minerals, proteins, essential fatty acids, [5][6][7][8][9][10][11][12][13][14][15][16][17] taking in consideration the type skin as well.…”

Section: Discussionmentioning

confidence: 99%

The role of diet in maintaining healthy skin

Paravina¹

2018

JDC

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Introduction: Skin is of crucial importance in the human system. There are numerous factors that affect its appearance and function. Various skin conditions and fast aging are manifestation of certain disturbances. Aim: To give information to dermatologists and nutritionists about the role of the diet in maintaining healthy skin and the usage of knowledge in everyday practice and working with patients, a detailed analysis of available literature is performed on the impact and mechanisms of various food ingredients on the role and appearance of skin. The data will be useful to the readers of this text. Data: The data on the nutrients that affect healthy skin are obtained: The quality, health and beauty of the skin are affected by various vitamins, minerals, proteins, as well as by other nutrients. Some foods make skin shiny and healthy, but there is also bad diet for skin, as well as foods with harmful effects, depending on skin type. Discussion: It is of crutial importance to protect skin from negative factors. In order to provide for normal functioning of the skin it is necessary to incorporate various foods of animal or plant origin, taking in consideration skin type as well. Conclusion: It is clear why full attention should be paid to skin, its health, functions and appearance. Adequate diet is of crutial importance, with appropriate use of vitamins, minerals, proteins and other nutrients paying attention to possible benefitial effects of certain foods, adjusted to the skin type. This should be applied in everyday practice in working with patients.

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The influence of selected ingredients of dietary supplements on skin condition

Cited by 34 publications

References 28 publications

The Role of Pomelo Peel Extract for Experimentally Induced Wound in Diabetic Rats

The Role of Pomelo Peel Extract for Experimentally Induced Wound in Diabetic Rats

Original paper Insulin resistance in severe acne vulgaris

The role of diet in maintaining healthy skin

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