2021
DOI: 10.1111/ijcp.14984
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The influence of sex on ischemic stroke incidence, therapeutic procedures and in‐hospital mortality: Results of the Spanish National Hospital Discharge

Abstract: Background Previous research has revealed sex‐related differences in outcomes for people admitted to hospitals for ischemic stroke. We aimed to analyse the incidence, use of invasive procedures and in‐hospital outcomes of ischemic stroke in Spain (2016‐2018) using the Spanish National Hospital Discharge Database. We sought sex‐related differences in incidence and in‐hospital outcomes over time. Methods We estimated the incidence of ischemic stroke in men and women. We analysed comorbidities (Charlson's comorbi… Show more

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Cited by 4 publications
(3 citation statements)
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“…Interestingly, we found that age-standardized prevalence and incidence rates in males were lower than in females, suggesting that women are more likely to have ischemic stroke than men. This finding contradicts results from previous studies ( 25 , 26 ). Racial disparity and age variability might probably explain this paradox.…”
Section: Discussioncontrasting
confidence: 99%
“…Interestingly, we found that age-standardized prevalence and incidence rates in males were lower than in females, suggesting that women are more likely to have ischemic stroke than men. This finding contradicts results from previous studies ( 25 , 26 ). Racial disparity and age variability might probably explain this paradox.…”
Section: Discussioncontrasting
confidence: 99%
“…The 2020 report included total number of female and male stroke cases, but no sex-specific treatment details 39 . The Sentinel Stroke National Audit Programme (SSNAP) Eighth Annual Report also lacked information regarding protected characteristics 41 , as did the 2020 Irish National Audit of Stroke report 42 . To fully investigate equity of AIS treatments, registry studies and audits should automatically report patient protected characteristics and collect and report data on factors that might confound the relationship between sex and thrombectomy use, so that future systematic reviews can adjust for relevant factors, including age and time since symptom onset to presentation at medical services.…”
Section: Discussionmentioning
confidence: 99%
“… 23 , 24 The male gender was a significantly stronger predictor of ischemic stroke since males have a higher prevalence of cardiovascular conditions such as higher blood pressure 25 and stroke. 26 , 27 The EPIC Potsdam Study 28 indicated that almost 60% of ischemic stroke risk could be attributed to hypertension, hypercholesterolemia, and cigarette smoking. There is a strong dose–response relationship between the number of cigarettes smoked and the risk of ischemic stroke, cigarette smoking causes a twofold increase in the risk of ischemic stroke.…”
Section: Discussionmentioning
confidence: 99%