The influence of size or number of biopsies on rapid urease test results: a prospective evaluation

Laine, Loren; Chun, David S.; Stein, Craig; El-Beblawi, Ihab; Sharma, Vinod; Chandrasoma, Parakrama

doi:10.1016/s0016-5107(96)70260-2

Cited by 64 publications

(24 citation statements)

References 6 publications

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“…Guell et al [9] advocated that a delayed test should be performed to rule out H. pylori infection. Laine et al [24] demonstrated that increase in size or number of biopsies could hasten the development of positive RUT. Siddique et al [10] reported that the sensitivity of RUT improved significantly when the gastric antral biopsy number increased from 1 to 4.…”

Section: Discussionmentioning

confidence: 99%

Increasing Biopsy Number and Sampling from Gastric Body Improve the Sensitivity of Rapid Urease Test in Patients with Peptic Ulcer Bleeding

et al. 2014

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Section: Discussionmentioning

confidence: 99%

Increasing Biopsy Number and Sampling from Gastric Body Improve the Sensitivity of Rapid Urease Test in Patients with Peptic Ulcer Bleeding

et al. 2014

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“…Different ways to improve the sensitivity of the tests include: (i) increasing the urea concentration from 2 to 10% (41), (ii) incubating at a higher temperature (37°C) (287,595), and (iii) suppression of the buffer (15), while the size of the biopsy does not appear to be important (286,594). Unbuffered media have a limited shelf life (Ͻ5 days at 4°C) (406).…”

Section: Urease Testsmentioning

confidence: 99%

Helicobacter pyloriDetection and Antimicrobial Susceptibility Testing

2007

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SUMMARY The discovery of Helicobacter pylori in 1982 was the starting point of a revolution concerning the concepts and management of gastroduodenal diseases. It is now well accepted that the most common stomach disease, peptic ulcer disease, is an infectious disease, and all consensus conferences agree that the causative agent, H. pylori, must be treated with antibiotics. Furthermore, the concept emerged that this bacterium could be the trigger of various malignant diseases of the stomach, and it is now a model for chronic bacterial infections causing cancer. Most of the many different techniques involved in diagnosis of H. pylori infection are performed in clinical microbiology laboratories. The aim of this article is to review the current status of these methods and their application, highlighting the important progress which has been made in the past decade. Both invasive and noninvasive techniques will be reviewed.

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“…The low specificity of the H. pylori ascertainment method may be explained, among other factors, by cross-reactivity with other non -H. pylori infections, by lack of detection of H. pylori in the biopsies (sample error; refs. [35][36][37][38], or by spontaneous eradication. Nevertheless, only a minority of infected individuals could eradicate the infection spontaneously (39), except when the development of gastric mucosal atrophy renders the gastric environment hostile to the bacterium.…”

Section: Discussionmentioning

confidence: 99%

Gastric Cancer is Related to Early Helicobacter pylori Infection in a High-Prevalence Country

Ferreccio

Rollán

Harris

et al. 2007

Cancer Epidemiology, Biomarkers &Amp; Prevention

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Background and Aims: Chile ranks fifth in the world among countries with the highest incidence of gastric cancer. The aim was to quantify the association between Helicobacter pylori infection and gastric cancer mortality at the county of residence. Methods: A cross-sectional household survey, a probability sample of the Chilean adult population, provided 2,615 participants in whom serum H. pylori IgG antibodies were measured (ELISA). The spatial pattern of 48,367 deaths due to gastric cancer which occurred from 1985 to 2002 was analyzed using a hierarchical Poisson regression model; 333 counties were categorized as low, medium, and high gastric cancer mortality with median gastric cancer death rates of 11.4, 19.1, and 26.0 per 100,000 inhabitants, respectively. The association between H. pylori positivity and gastric cancer mortality in the county of residence was assessed by multivariate Poisson regression for complex samples.

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The influence of size or number of biopsies on rapid urease test results: a prospective evaluation

Cited by 64 publications

References 6 publications

Increasing Biopsy Number and Sampling from Gastric Body Improve the Sensitivity of Rapid Urease Test in Patients with Peptic Ulcer Bleeding

Increasing Biopsy Number and Sampling from Gastric Body Improve the Sensitivity of Rapid Urease Test in Patients with Peptic Ulcer Bleeding

Helicobacter pyloriDetection and Antimicrobial Susceptibility Testing

Gastric Cancer is Related to Early Helicobacter pylori Infection in a High-Prevalence Country

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