The Influence of the Genotype of Stud Bulls of Holstein Breed on the Level of Some Indicators of Nitrogen Metabolism of Offspring in Western Siberia Region

Abstract

The results of studies of indicators of nitrogen metabolism in the blood serum of the descendants of four bulls at the age of 12-13 months are presented. The studies were conducted in the South of Western Siberia at Vaganovo OJSC on the livestock population of Holstein breed. The creatinine concentration in the blood serum samples of the sons was determined using a set of reagents from Vector-Best (Russia). In the regions of animal breeding, constant monitoring of water, soil, feed, animal organs and tissues is carried out. It was established that in the areas in which the studied breeds were bred, the content of macro- and microelements did not exceed the MPC. The level of serum creatinine in the examined animals on average for all groups of sons was 308.2 ± 24.1 μmol / L, which exceeds the generally accepted values of this indicator. However, taking into account age and sex and breed characteristics, taking into account data on the overall health of the animals examined, information on the ecological well-being of the breeding zone, the results can be considered as reference values for healthy Holstein bulls in Western Siberia. It was shown that in the blood serum of the sons of some fathers, the creatinine content was 1.7 times higher (364.2 ± 52.7 μmol / L) than in the descendants of other manufacturers (p> 0.95). A group of half-siblings was found, which were characterized by a low hereditary predisposition to creatinine content. Discovered differences in the creatinine content in the blood serum of sons reflect the differentiation of bulls and indicate genetically determined features of the functioning of the homeostasis system. In this case, most likely, there is a different ability of descendants to adapt to environmental and climatic conditions.

Hereditary definiteness of aspartate aminotransferase level in Holstein cattle

“…Исключение составляют пролин, треонин и лизин. Важность участия АсТ в белковом и азотистом обменах подчеркивается тем фактом, что аспартаттрансаминаза в силу экспрессии во множестве клеточных компартментов является основным циркулирующим ферментом in vivo, тем самым приобретая особую роль в процессах роста и формирования продуктивных признаков у крупного рогатого скота [9,10]. Определённое значение имеют реакции глицеронеогенеза, катализируемые АсТ в адипоцитах жировой ткани [11,12].…”