The article presents the results of experiments to study the effect of an organomineral supplement containing a soluble complex of Fe, Mn, Zn, Cu, Co, Se, and I with amino acid derivatives on some biochemical parameters of rabbit blood. It was found that the mineral supplement in the form of chelates did not have a negative effect on the body of the rabbits. The main indicators of protein metabolism characterized the normal state of the body of rabbits, which drank a mineral supplement with water, which as a result was confirmed by a higher level of protein metabolism. Thus, the total protein content in the blood serum of the experimental animals was at the level of 60.5±3.6 g / l, which exceeded the control group by 6.32 %. The content of albumins and globulins increased by 9.79 and 4.37%, respectively. In the body of rabbits of the experimental group, the level of glucose, as an energy source for ensuring metabolic processes, increased by 35.56 % (P<0.01) compared to the control. However, all changes in the studied biochemical parameters of the blood occurred within the physiological norm. The use of a complex of mineral substances promotes better assimilation of feed, prevents mineral deficiency, improves metabolism, accelerates growth and ultimately increases the productivity of animals.